BioLegend 102619 PerCP/Cyanine

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BioLegend  102619  PerCP/Cyanine5.5 anti-mouse CD36
产品简介：
产品品牌：BioLegend
产品货号：102619
产品名称：BioLegend  102619  PerCP/Cyanine5.5 anti-mouse CD36
产品规格：102619

产品说明：
Clone  HM36 (See other available formats)
Regulatory Status   RUO
Other Names  FAT, gpIIIb, gpIV
Isotype  Armenian Hamster IgG

描述
CD36是一种85 kD糖蛋白，也称为FAT，gpIIIb或gpIV。它是B类清除受体家族的成员，在血小板，单核细胞，巨噬细胞，微血管系统，树突状细胞和乳腺内皮细胞上表达。据报道，CD36 的主要配体是氧化的低密度脂蛋白、阴离子磷脂和胶原蛋白 I、IV 和 V.CD36 充当清除受体，从而促进凋亡中性粒细胞和其他凋亡小细胞的去除，以及清除有缺陷的红细胞。
CD36 is a 85 kD glycoprotein, also known as FAT, gpIIIb, or gpIV. It is a member of the class B scavenger receptor family, expressed on platelets, monocytes, macrophages, megakaryocytes, microvasculature, dendritic cells and mammary endothelial cells. The primary ligands for CD36 have been reported to be oxidized low density lipoprotein, anionic phospholipids, and collagens I, IV, and V. CD36 acts as a scavenger receptor thus promoting the removal of apoptotic neutrophils and other apoptotic bodies, as well as clearance of defective erythrocytes.

Product Details
Isotype Control   PerCP/Cyanine5.5 Armenian Hamster IgG Isotype Ctrl
Verified Reactivity  Mouse
Antibody Type  Monoclonal
Host Species  Armenian Hamster
Immunogen  Full length version of the protein
Formulation  
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography and conjugated with PerCP/Cyanine5.5 under optimal conditions.
Concentration   0.2 mg/ml
Storage & Handling  
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application   FC - Quality tested
Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is =1.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Excitation Laser    Blue Laser (488 nm)
Additional Product Notes
BioLegend is in the process of converting the name PerCP/Cy5.5 to PerCP/Cyanine5.5. The dye molecule remains the same, so you should expect the same quality and performance from our PerCP/Cyanine5.5 products. Contact Technical Service if you have any questions.

Antigen Details
Structure  Scavenger receptor superfamily, 85 kD
Distribution
Platelets, monocytes, macrophages, microvascular and mammary endothelial cells
Function
Scavenger receptor, recognition and phagocytosis of apoptotic neutrophils, adhesion
Ligand/Receptor   Oxidized low density lipoprotein, anionic phospholipids, collagen I, IV, and V
Cell Type   Endothelial cells, Macrophages, Monocytes, Platelets
Biology Area   Immunology, Innate Immunity
Molecular Family  CD Molecules

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