- ￥3870 - 25190
- Sino Biological
- 56956-M07E
- 北京
- 2026年01月23日
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- 详细信息
- 文献和实验
- 技术资料
- 库存：
99
- 英文名：
PPARA Protein, Mouse, Recombinant (His Tag)
- 保质期：
12个月
- 供应商：
北京义翘神州科技股份有限公司
- 保存条件：
-20℃ to -80℃
- 规格：
50 µg/500 µg
| 规格： | 50 µg | 产品价格： | ￥3870.0 |
|---|---|---|---|
| 规格： | 500 µg | 产品价格： | ￥25190.0 |
≥ 90 % as determined by SDS-PAGE.
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
生物活性
Testing in progress
蛋白构建
A DNA sequence encoding the Mouse PPARA (P23204) (Thr200-Tyr468) was expressed, with a polyhistidine tag at the N-terminus.
表达宿主
E.coli
种属
Mouse
预测 N 端
His
分子量
The recombinant Mouse PPARA consists of 276 amino acids and predicts a molecular mass of 31.49 kDa.
缓冲液
Lyophilized from sterile 50mM Tris, 10% glycerol, pH 8.0.
Please contact us for any concerns or special requirements.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the hard copy of CoA.
运输方式
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
稳定性 & 储存条件
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
复溶
A hardcopy of datasheet with reconstitution instructions is sent along with the products. Please refer to it for detailed information.
PPARA Protein, Mouse, Recombinant (His Tag): 别称
4933429D07Rik Protein, Mouse; AW742785 Protein, Mouse; Nr1c1 Protein, Mouse; Ppar Protein, Mouse; PPAR-alpha Protein, Mouse; PPARalpha Protein, Mouse
PPARA 背景信息
Peroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers; this term arises because they induce an increase in the size and number of peroxisomes. Peroxisomes are subcellular organelles found in plants and animals that contain enzymes for respiration and for cholesterol and lipid metabolism. The action of peroxisome proliferators is thought to be mediated via specific receptors, called PPARs, which belong to the steroid hormone receptor superfamily. PPARs affect the expression of target genes involved in cell proliferation, cell differentiation and in immune and inflammation responses. Three closely related subtypes (alpha, beta/delta, and gamma) have been identified. This gene encodes the subtype PPAR-alpha, which is a nuclear transcription factor. Multiple alternatively spliced transcript variants have been described for this gene, although the full-length nature of only two has been determined.
Cancer Immunotherapy
Immune Checkpoint
Immunotherapy
Targeted Therapy
全称
peroxisome proliferator-activated receptor alpha
Related Pathways
MAPK-Erk Pathway
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美国研究人员日前报告说，他们发现小鼠体重与一种名为FIH的蛋白质有关，这一发现为研制减肥药物提供了新思路。 美国加州大学圣迭戈分校的研究人员在新一期美国《细胞—代谢》（Cell Metabolism）杂志上报告说，FIH是一种负责调节缺氧反应的蛋白质，缺乏这种蛋白质的小鼠会保持苗条和健康，哪怕它们进食的是高脂肪食物。 在实验过程中，研究人员通过基因技术培育出缺乏FIH蛋白质的实验鼠，然后让它们和普通实验鼠同时进食脂肪含量高达60%的食物。结果发现，缺乏FIH蛋白质的实验鼠平均身材明显比普通
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