Biodragon博奥龙WB明星产品B8010现货促销Act

Biodragon博奥龙WB明星产品B8010现货促销Actin beta(4L2) Rabbit Monoclonal Antibody博奥龙Biodragon独家总代理19121878899上海睿安生物

产品基本信息

• 产品货号B8010
• 别名:ACTB;Actin; cytoplasmic 1;Beta-actin;Actin β;β-Actin;Beta actin;B actin;actin Beta
• 产品名称:Actin beta (4L2) Rabbit Monoclonal Antibody
• 类别:抗体产品
• 基因名称:ACTB
• 蛋白名称:Actin cytoplasmic 1
• 推荐应用:WB,ELISA
• 反应种属:Human,Mouse,Rat
• 存储缓冲液:PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
• Human Gene ID60
• Human Swissprot No.P60709
• Mouse Gene ID11461
• Mouse Swissprot No.P60710
• Rat Gene ID81822
• Rat Swissprot No.P60711
• 免疫原:Synthesized peptide derived from human protein. AA range:1-100
• 特异性:endogenous
• 稀释度：WB 1:500-2000, ELISA 1:20000
• 参考分子量:42kDa
• 预测分子量:42kDa
• 运输及保存条件:Biological ice bag transportation. Store at -20°C for at least 12 months(Do not lower than -25°C). Avoid freeze/thaw cycles
• 宿主:Monoclonal Rabbit IgG1, Kappa
• 背景介绍:This gene encodes one of six different actin proteins. Actins are highly conserved proteins that are involved in cell motility, structure, and integrity. This actin is a major constituent of the contractile apparatus and one of the two nonmuscle cytoskeletal actins. [provided by RefSeq, Jul 2008]
• 细胞定位:Cytoplasm, cytoskeleton . Nucleus . Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
• 表达:B-cell lymphoma,Brain,Cajal-Retzius cell,Eye,Fetal brain cortex,Foreskin,Hepatocellular car
• 功能:disease:Defects in ACTB are a cause of dystonia juvenile-onset (DYTJ) [MIM:607371]. DYTJ is a form of dystonia with juvenile onset. Dystonia is defined by the presence of sustained involuntary muscle contraction, often leading to abnormal postures. DYTJ patients manifest progressive, generalized, dopa-unresponsive dystonia, developmental malformations and sensory hearing loss.,function:Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.,miscellaneous:In vertebrates 3 main groups of actin isoforms, alpha, beta and gamma have been identified. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins coexist in most cell types as components of the cytoskeleton and as mediators of internal cell motility.
• 纯化:Protein A

Whole cell lysates were separated by 10% SDS-PAGE, and the membrane was blotted with β-actin Rabbit Monoclonal Antibody. The HRP-conjugated Goat anti-Rabbit IgG(H + L) antibody was used to detect the antibody. Lane 1:Hela Predicted band size: 42kDa Observed band size: 42kDa

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