S1pr2蛋白|诺维吉库斯鼠S1pr2蛋白|诺维吉库斯鼠S1

Research Areas

Epigenetics and Nuclear Signaling

Uniprot ID

P47752

Gene Names

S1pr2

Alternative Name(s)

(S1P receptor 2)(S1P2)(AGR16)(Endothelial differentiation G-protein coupled receptor 5)(G-protein coupled receptor H218)(Sphingosine 1-phosphate receptor Edg-5)(S1P receptor Edg-5)

Lead Time

18-23 business days

Organism

Rattus norvegicus (Rat)

Source

in vitro E.coli expression system

Expression Region

1-352aa

Protein Length

Full Length

Tag Info

C-terminal 10xHis-tagged

Target Protein Sequence

MGGLYSEYLNPEKVQEHYNYTKETLDMQETPSRKVASAFIIILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGPVTLSLTPLQWFAREGSAFITLSASVFSLLAIAIERQVAIAKVKLYGSDKSCRMLMLIGASWLISLILGGLPILGWNCLDHLEACSTVLPLYAKHYVLCVVTIFSVILLAIVALYVRIYFVVRSSHADVAGPQTLALLKTVTIVLGVFIICWLPAFSILLLDSTCPVRACPVLYKAHYFFAFATLNSLLNPVIYTWRSRDLRREVLRPLLCWRQGKGATGRRGGNPGHRLLPLRSSSSLERGLHMPTSPTFLEGNTVV

MW

41.6 kDa

Purity

Greater than 85% as determined by SDS-PAGE.

Endotoxin

Not test.

Biological_Activity

/

Form

Liquid or Lyophilized powder

Buffer

If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Storage

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.

Relevance

Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P) . S1P is a bioactive lysophospholipid that elicits diverse physiological effects on most types of cells and tissues . Receptor for the chemokine-like protein FAM19A5 . Mediates the inhibitory effect of FAM19A5 on vascular smooth muscle cell proliferation and migration .

Function

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