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- 文献和实验
- 技术资料
- 保存条件:
We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃.
- 保质期:
Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.
- 英文名:
Recombinant Mouse Troponin T, cardiac muscle (Tnnt2)
- 库存:
200
- 供应商:
武汉华美生物工程有限公司
- 规格:
20μg
英文名称:
Recombinant Mouse Troponin T, cardiac muscle (Tnnt2)品名简称:
Recombinant Mouse Tnnt2 protein货号:
CSB-EP024016MOb1规格:
20μg价格:
2328LC-MS/Western Blot:
/SDS-PAGE:
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.纯度:
Greater than 90% as determined by SDS-PAGE.内毒素:
Not test生物活性:
/基因名:
Tnnt2Uniprot No.:
P50752别名:
(TnTc)(Cardiac muscle troponin T)(cTnT)种属:
Mus musculus (Mouse)蛋白长度:
Full Length of Mature Protein来源:
E.coli分子量:
43.1 kDa表达区域:
2-301aa氨基酸序列:
SDAEEVVEEYEEEQEEEDWSEEEEDEQEEAVEEEEAGGAEPEPEGEAETEEANVEEVGPDEEAKDAEEGPVEDTKPKPSRLFMPNLVPPKIPDGERVDFDDIHRKRVEKDLNELQTLIEAHFENRKKEEEELISLKDRIEKRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAEDEARKKKALSNMMHFGGYIQKQAQTERKSGKRQTEREKKKKILAERRKALAIDHLNEDQLREKAKELWQSIHNLEAEKFDLQEKFKQQKYEINVLRNRINDNQKVSKTRGKAKVTGRWK蛋白标签:
N-terminal 10xHis-tagged and C-terminal Myc-tagged产品提供形式:
Liquid or Lyophilized powder缓冲液:
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.储存条件:
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.保质期:
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.货期:
13-23 business days注意事项:
Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.功能1:
Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.功能2:
/文献:
"Identification of a functionally critical protein kinase C phosphorylation residue of cardiac troponin T." Sumandea M.P., Pyle W.G., Kobayashi T., de Tombe P.P., Solaro R.J. J. Biol. Chem. 278:35135-35144(2003)研究领域:
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文献和实验Expanding Mouse Ventricular Cardiomyocytes Through GSK‐3 Inhibition
Primary antibodies against: Cardiac troponin T (cTnT, mouse monoclonal, NeoMarkers, Ms‐295, 0.2 mg/ml, 1:250
RNA测序数据与公共数据库信息,利用多个前沿大语言模型对10,000多个潜在靶点进行优先排序与提名,并通过1,000次独立模拟排除AI幻觉等风险,整个流程耗时不到数周,远快于传统手动方法。作为概念验证,团队开发出靶向GPNMB的CAR-T细胞疗法,临床前实验证实其在黑色素瘤、白血病和结直肠癌等多种癌症小鼠模型中均表现出强大的肿瘤杀伤活性。该AI框架具有模块化、不依赖疾病类型的特点,可兼容不同数据集与未来的新模型,研究团队已将其方法公开,并计划继续完善GPNMB CAR-T疗法以推进
合作,近期在Aging Cell发表了一篇研究。该研究通过整合单细胞转录组、单核转录组和空间转录组测序,系统描绘了小鼠肝脏衰老过程中免疫微环境的时空动态演变,发现CD8⁺ T细胞耗竭具有门静脉区特异性空间富集特征,并鉴定出门静脉旁肝细胞中的LPIN1分子是诱导T细胞耗竭的关键调控因子。该现象在多种人类肝脏疾病中得到验证,为延缓肝脏衰老相关免疫功能障碍及治疗年龄相关肝病提供了潜在新靶点。 02 靶点:ZDHHC20 应用:为临床
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