CLDN6/CLDN6蛋白Recombinant Human

纯度：

The purity information is not available for VLPs proteins.

基因名：

CLDN6

Uniprot No.：

P56747

别名：

(Skullin)

种属：

Homo sapiens (Human)

蛋白长度：

Full Length

来源：

Mammalian cell

分子量：

25.1 kDa

表达区域：

1-220aa

氨基酸序列：

MASAGMQILGVVLTLLGWVNGLVSCALPMWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTGQMQCKVYDSLLALPQDLQAARALCVIALLVALFGLLVYLAGAKCTTCVEEKDSKARLVLTSGIVFVISGVLTLIPVCWTAHAIIRDFYNPLVAEAQKRELGASLYLGWAASGLLLLGGGLLCCTCPSGGSQGPSHYMARYSTSAPAISRGPSEYPTKNYV

蛋白标签：

C-terminal 10xHis-tagged (This tag can be tested only under denaturing conditions)

产品提供形式：

Lyophilized powder

缓冲液：

Lyophilized from a 0.2 μm filtered PBS, 6% Trehalose, pH 7.4

货期：

3-7 business days

注意事项：

The VLPs are expressed from human 293 cells (HEK293).Mix the sample gently by repeatedly pipetting it up and down. Do not vortex.Repeated freezing and thawing is not recommended.Store the protein at -20℃/-80℃ upon receiving it, and ensure to avoid repeated freezing and thawing, otherwise, it will affect the protein activity. The immunization strategy should be optimized (antigen dose, regimen and adjuvant).

功能：

"Claudin association with CD81 defines hepatitis C virus entry." Harris H.J., Davis C., Mullins J.G., Hu K., Goodall M., Farquhar M.J., Mee C.J., McCaffrey K., Young S., Drummer H., Balfe P., McKeating J.A. J. Biol. Chem. 285:21092-21102(2010)

内毒素：

Less than 1.0 EU/ug as determined by LAL method.

SDS-PAGE:

CSB-MP005508HU(A4) is detected by Mouse anti-6*His monoclonal antibody.

LC-MS Image Description/Western Blot:

The presence of VLP-like structures was confirmed by TEM

Product types:

MP-VLP Transmembrane Protein & Active Protein & In Stock Protein

Biological_Activity:

Measured by its binding ability in a functional ELISA. Immobilized Human CLDN6 at 10 μg/mL can bind Anti-CLDN6/9 recombinant antibody (CSB-RA005508MA1HU), the EC50 is 1.501-2.035 ng/mL

Research Areas:

Cancer

Reconstitution:

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein indeionized sterile water to a concentration of 0.1-1.0 mg/mL.Aliquot for long-term storage at -80℃. Solubilize for 60 minutes at room temperature with occasional gentle mixing. Avoid vigorous shaking or vortexing.

Reference:

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Function:

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