小鼠细胞因子信号转导抑制因子1(SOCS-1)ELISA试剂
盒【Mouse suppressors of cytokine signaling 1(SOCS-1)ELISA Kit】- ￥2500 - 3600
- CUSABIO
- 15.6pg/mL
- 武汉
- CSB-E17346m
- 2025年07月30日
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- 详细信息
- 文献和实验
- 技术资料
- 供应商：
武汉益普生物科技有限公司
- 检测范围：
15.6pg/mL
- 检测方法：
Sandwich
- 应用：
Signal Transduction
- 适应物种：
Mus musculus (Mouse)
- 样本：
serum, plasma, tissue homogenates
- 规格：
96T/48T
| 规格： | 96T | 产品价格： | ￥3600.0 |
|---|---|---|---|
| 规格： | 48T | 产品价格： | ￥2500.0 |
| Product Name |
Mouse suppressors of cytokine signaling 1(SOCS-1)ELISA Kit |
| Chinese Name |
小鼠细胞因子信号转导抑制因子1（SOCS-1）ELISA Kit |
| Code |
CSB-E17346m |
| Alternative Names |
Socs1 ELISA Kit; Cish1 ELISA Kit; Ssi1 ELISA Kit; Suppressor of cytokine signaling 1 ELISA Kit; SOCS-1 ELISA Kit; JAK-binding protein ELISA Kit; JAB ELISA Kit; STAT-induced STAT inhibitor 1 ELISA Kit; SSI-1 ELISA Kit |
| Target Name |
suppressors of cytokine signaling 1(SOCS-1) |
| Abbreviation |
SOCS-1 |
| Uniprot No. |
O35716 |
| Species |
Mus musculus (Mouse) |
| Sample Types |
serum, plasma, tissue homogenates |
| Detection Range |
62.5pg/mL-4000pg/mL |
| Sensitivity |
15.6pg/mL |
| Assay Principle |
quantitative |
| Measurement |
Sandwich |
| Assay Time |
1-5h |
| Sample Volume |
50-100ul |
| Detection Wavelength |
450nm |
| Research Area |
Signal Transduction |
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文献和实验In Vitro Ubiquitination of Cytokine Signaling Components
The eight SOCS (Suppressor of Cytokine Signaling) proteins encoded in the human genome all contain a C-terminal domain, the SOCS box, that allows them to function as E3 ubiquitin ligases and thereby catalyze the ubiquitination of components
Detection of Endogenous SOCS1 and SOCS3 Proteins by Immunoprecipitation and Western Blot Analysis
The suppressors of cytokine signalling (SOCS) protein family consist of eight members (SOCS 1–7, and CIS). SOCS1 and SOCS3 are the best-studied family members and have been shown to act as negative feedback inhibitors of the JAK/STAT
, we have demonstrated in vascular endothelial cells that activation of Epac1 is necessary for cAMP-mobilizing agents to trigger the induction of the gene-encoding suppressor of cytokine signaling-3 (SOCS-3), a potent inhibitor of interleukin (IL)-6 signaling
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