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- 详细信息
- 文献和实验
- 技术资料
- 供应商:
武汉益普生物科技有限公司
- 检测范围:
0.039ng/mL
- 检测方法:
Sandwich
- 应用:
Epigenetics and Nuclear Signaling
- 适应物种:
Mus musculus (Mouse)
- 样本:
serum, plasma, tissue homogenates
- 规格:
96T/48T
| 规格: | 96T | 产品价格: | ¥3600.0 |
|---|---|---|---|
| 规格: | 48T | 产品价格: | ¥2500.0 |
| Product Name |
Mouse NAD-dependent deacetylase sirtuin-1(Sirt1)ELISA Kit |
| Chinese Name |
小鼠NAD依赖性蛋白脱乙酰酶sirtuin-1(SIRT1)ELISA Kit |
| Code |
CSB-E16187m |
| Alternative Names |
Sirt1 ELISA Kit; Sir2l1 ELISA Kit; NAD-dependent protein deacetylase sirtuin-1 ELISA Kit; EC 2.3.1.286 ELISA Kit; NAD-dependent protein deacylase sirtuin-1 ELISA Kit; EC 2.3.1.- ELISA Kit; Regulatory protein SIR2 homolog 1 ELISA Kit; SIR2-like protein 1 ELISA Kit; SIR2alpha ELISA Kit; Sir2 ELISA Kit; mSIR2a) [Cleaved into: SirtT1 75 kDa fragment ELISA Kit; 75SirT1)] ELISA Kit |
| Target Name |
sirtuin (silent mating type information regulation 2 homolog) 1 (S. cerevisiae) |
| Abbreviation |
SIRT1 |
| Uniprot No. |
Q923E4 |
| Species |
Mus musculus (Mouse) |
| Sample Types |
serum, plasma, tissue homogenates |
| Detection Range |
0.156ng/mL-10ng/mL |
| Sensitivity |
0.039ng/mL |
| Assay Principle |
quantitative |
| Measurement |
Sandwich |
| Assay Time |
1-5h |
| Sample Volume |
50-100ul |
| Detection Wavelength |
450nm |
| Research Area |
Epigenetics and Nuclear Signaling |
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文献和实验Sirtuins are a class of enzymes with important functions in regulation aging, metabolism, and genome stability. They were originally known as nicotinamide adenine dinucleotide (NAD)-dependent protein lysine deacetylases. However, recently
In Vivo Measurement of the Acetylation State of Sirtuin Substrates as a Proxy for Sirtuin Activity
acetylation status of select sirtuin substrates in vivo remains an important tool for evaluating changes in sirtuin activity. Here, we describe how to perform the analysis of the acetylation status of key SIRT1 and SIRT3 targets in rodent tissues and cultured
Methods to Investigate the Role of SIRT1 in Endothelial Senescence
Sirtuins are a family of proteins with NAD+ -dependent deacetylase or mono-ADP-ribosyltransferase activity. SIRT1, the mammalian ortholog most closely related to Sir2 (the first gene of this family discovered in yeast), exhibits anti
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