- ￥6300
- GeneTex
- 美国
- GTX60881
- 2025年07月11日
- WB, ICC/IF, ELISA
- Rabbit
- Human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
An acetyl-peptide corresponding to Acetyl-Histone H3 (Lys36).
- 亚型：
IgG
- 形态：
Liquid
- 保存条件：
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
- 克隆性：
Monoclonal
- 标记物：
Unconjugated
- 适应物种：
Human
- 保质期：
12 months from the shipping date of the product.
- 抗原来源：
Human
- 目录编号：
GTX60881
- 级别：
Primary Antibodies
- 库存：
Available
- 供应商：
GeneTex
- 宿主：
Rabbit
- 应用范围：
WB, ICC/IF, ELISA
- 浓度：
Batch dependent (Please refer to the vial label for the specific concentration.)
- 靶点：
This antibody reacts to Histone H3 acetylated at Lysine 36 (K36ac), and is not affected by the phosphorylation of neighboring Ser31. No cross reactivity with other acetylated Lysines in histone H3.
- 抗体英文名：
Histone H3K36ac (Acetyl Lys36) antibody [RM154]
- 抗体名：
Histone H3K36ac (Acetyl Lys36) 抗体 [RM154]
- 规格：
100 μg
The GTX60881 reacts to Histone H3 acetylated at Lysine 36 (K36ac), and is not affected by the phosphorylation of neighboring Ser31. No cross reactivity with acetylated Lysine 4 (K4ac), Lysine 9 (K9ac), Lysine 14 (K14ac), Lysine 18 (K18ac), Lysine 23 (K23ac), Lysine 27 (K27ac), Lysine 56 (K56ac), lysine 79 (K79ac), or Lysine 122 (K122) in histone H3.
WB analysis of acid extracts from HeLa cells untreated (-) or treated with sodium butyrate (+) using GTX60881 Histone H3K36ac (Acetyl Lys36) antibody [RM154].
Dilution : 1μg/ml
ICC/IF analysis of HeLa cells treated with sodium butyrate using GTX60881 Histone H3K36ac (Acetyl Lys36) antibody [RM154].
Red : Primary antibody
Green : Actin
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文献和实验9.19 Nature：揭示组蛋白标记 H3K36me2 招募 DNMT3A 并影响基因间 DNA 甲基化
中心、洛克菲勒大学和加拿大麦吉尔大学等研究机构的研究人员报道 NSD1 介导的 H3K36me2 是在基因间区域招募 DNMT3A 和维持 DNA 甲基化所必需的。这项新的研究揭示了一种跨染色质调节途径，这种调节突进将异常的基因间 CpG 甲基化与人类肿瘤生长和过度发育相关联在一起。原文检索：The histone mark H3K36me2 recruits DNMT3A and shapes the intergenic DNA methylation landscape ② Nature 突破
Identifying Differential Histone Modification Sites from ChIPseq Data
cell (NPC). We demonstrated that the H3K27me3 DHMSs identified by our approach are of high sensitivity, specificity, and technical reproducibility. ChIPDiff was further applied to uncover the differential H3K4me3 and H3K36me3 sites between different
ChIP数据分析：ChIP结果图来PK，谁才是发文的香饽饽？
不同温度条件对组蛋白H3K36me3修饰的整体丰度产生影响。 （Histone H3 lysine 36 methylation affects temperature-induced alternative splicing and flowering in plants） 不同类型（T、M、N、P）样本的H3K27ac修饰分布差异，M组在整体及多个基因的H3K27ac修饰均高于T组。（图片来源：Enhancer Reprogramming Promotes
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