D-AP5 is a selective N-methyl-D-aspartate (NMDA) receptor antagonist that binds at glutamate site. D-AP5 is reported to be the most active form of AP5 and is used in the research of synaptic plasticity.
产品信息: 应用: FA 同义词: 2-APV, 5 Phosphononorvaline 配方:Crystalline solid 化学名称:(2R)-2-amino-5-phosphonopentanoic acid 分子式:C5H12NO5P 分子量:197.1 CAS号:79055-68-8 纯度:≥95% 储存条件:产品应保持在-20°C。 参考: Steele, R. J., & Morris, R. G. M. (1999). Delay‐dependent impairment of a matching‐to‐place task with chronic and intrahippocampal infusion of the NMDA‐antagonist D‐AP5. Hippocampus, 9(2), 118-136.
Morris, R. G. (1989). Synaptic plasticity and learning: selective impairment of learning rats and blockade of long-term potentiation in vivo by the N-methyl-D-aspartate receptor antagonist AP5. The Journal of neuroscience,9(9), 3040-3057.
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