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- 2025年12月05日
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HIV-1 protease-IN-3
MCE 国际站：HIV-1 protease-IN-3
产品活性：HIV-1 protease-IN-3 (compound 14) 是一种强效的 HIV-1 蛋白酶抑制剂 (IC50=71 nM; EC50=0.86 μM)。
研究领域：Anti-infection | Metabolic Enzyme/Protease
作用靶点：HIV | HIV Protease
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文献和实验Identifying and Characterizing HIV Protease Inhibitors
HIV protease catalyzes the hydrolysis of specific peptide bonds of viral polyproteins, thus processing these polyproteins into their active components. These protein processing reactions are requisite for viral replication. Therefore, the HIV
In Vitro Translation to Study HIV Protease Activity
HIV-1 is an etiological agent of AIDS. One of the targets of the current anti-HIV-1 combination chemotherapy, called highly active antiretroviral therapy (HAART), is HIV-1 protease (PR), which is responsible for the processing of viral
A Conformationally Restricted -Strand HIV Protease Inhibitor
after the potent HIV protease inhibitor 2 , which together with a series of related derivatives was developed at Abbott Laboratories ( 11 ). This pseudopeptide contains a symmetrical diamino diol motif 8 (Fig. 2 ) flanked by Cbz-protected valine residues
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