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- 详细信息
- 技术资料
- 保存条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
- 英文名:
ALXN1007; Lendalizumab
- 库存:
货期:1-2天
- 供应商:
MedChemExpress LLC
- CAS号:
2210314-30-8
- 规格:
1 mg/5 mg/10 mg
| 规格: | 1 mg | 产品价格: | ¥3000.0 |
|---|---|---|---|
| 规格: | 5 mg | 产品价格: | ¥9000.0 |
| 规格: | 10 mg | 产品价格: | ¥14500.0 |
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Olendalizumab
CAS No. : 2210314-30-8
MCE 国际站:Olendalizumab
产品活性:Olendalizumab (ALXN1007) 是一种源自小鼠的人源化 IgG2-G4-κ 抗体,靶向补体蛋白 C5a (Ki=60 pM)。Olendalizumab 靶向补体炎症通路。并且,Olendalizumab 可用于研究由冠状病毒引起的补体介导的疾病。
作用靶点:Complement System
In Vitro: Olendalizumab can be used as an biotinylated capture reagent, with working concentration of 100 μg/mL in Bioaffy wash 1, while the AlexaFluor labeled anti-C5a clone 2942 is 4 μg/mL in Rexxip F.
The members of the complement system such as C3, C5a, C5b-9, including receptors such as C3aR and C5aR mediate the lung injury following viral infection. Moreover, C5/C5a is only non-silent complement in corona virus-induced lung injury. Olendalizumab is the potent C5a inhibitor.
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