Anti-MORF4L1 Polyclonal Antibo

产品简介

英文名称	Anti-MORF4L1 Polyclonal Antibody
中文名称	死亡因子4样蛋白1抗体
别名	MORF4L1;Eaf3;FWP006;HsT17725;MEAF3;MORFRG15;MRG15;S863-6;mortality factor 4 like 1
背景资料	Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction; tumor suppressor mediated growth arrest and replicative senescence; apoptosis; and DNA repair. The NuA4 complex ATPase and helicase activities seem to be; at least in part; contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Also component of the mSin3A complex which acts to repress transcription by deacetylation of nucleosomal histones. Required for homologous recombination repair (HRR) and resistance to mitomycin C (MMC). Involved in the localization of PALB2; BRCA2 and RAD51; but not BRCA1; to DNA-damage foci.
Swiss Prot	Q9UBU8
Gene ID	10933
亚细胞定位	Nucleus
宿主	Rabbit
克隆类型	Polyclonal Antibody
亚型	IgG
蛋白分子量	27/37/41kDa
稀释比例	WB 1:1000-3000. IHC 1:100-300.
免疫原	A synthetic peptide of Human MORF4L1
Public Immunogen Range	60-110/368aa
纯化方法	Affinity purification
储存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
保存	Store at -20°C. Avoid freeze / thaw cycles.
交叉反应	Human Rat Mouse
应用	WB IHC
规格	50ul 100ul
单位	支

备注：
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these methods.
温馨提示：
使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.
实验图

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