- ￥2750 - 4600
- Solarbio|ActivAb
- 北京
- K009444P
- 2025年08月19日
- WB;ELISA
- Rabbit
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Recombinant SARS-CoV-2 / 2019-nCoV Spike/RBD Protein
- 亚型：
IgG
- 保存条件：
Store at -20℃. Avoid freeze/thaw cycles.
- 克隆性：
Polyclonal Antibody
- 标记物：
Biotin，Cy3，Cy3.5，Cy5，Cy5.5，Cy7，FITC，HRP，RBITC，Solar Fluor 350，Solar Fluor 405，Solar Fluor 488，Solar Fluor 532，Solar Fluor 555，Solar Fluor 568，Solar Fluor 594，Solar Fluor 633，Solar Fluor 640，Solar Fluor 647，Solar Fluor 660，Solar Fluor 680，Solar Fluor 750
- 抗原来源：
Recombinant SARS-CoV-2 / 2019-nCoV Spike/RBD Protein
- 级别：
实验级别
- 库存：
现询
- 供应商：
北京索莱宝科技有限公司
- 宿主：
Rabbit
- 应用范围：
WB;ELISA
- 浓度：
WB 1:1000-5000. ELISA 1:5000-10000.
- 靶点：
SARS-CoV-2 (2019-nCoV) RBD
- 抗体英文名：
Anti-SARS-CoV-2 (2019-nCoV) Spike RBD Polyclonal Antibody
- 抗体名：
coronavirus spike Protein, 2019-nCoV, cov spike Protein, 2019-nCoV, novel coronavirus RBD Protein, 2019-nCoV, novel coronavirus s1 Protein, 2019-nCoV, novel coronavirus spike Protein, 2019-nCoV, RBD Protein, 2019-nCoV, S1 Protein, 2019-nCoV
- 规格：
50ul/100ul
| 规格： | 50ul | 产品价格： | ￥2750.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥4600.0 |
| 基本信息 | |
| 英文名称 | Anti-SARS-CoV-2 (2019-nCoV) Spike RBD Polyclonal Antibody |
| 宿主 | Rabbit |
| 克隆类型 | Polyclonal Antibody |
| 亚型 | IgG |
| 应用 | WB;ELISA |
| 稀释比例 | WB 1:1000-5000. ELISA 1:5000-10000. |
| 密度 | |
| 靶标 | SARS-CoV-2 (2019-nCoV) RBD |
| 别名 | coronavirus spike Protein, 2019-nCoV, cov spike Protein, 2019-nCoV, novel coronavirus RBD Protein, 2019-nCoV, novel coronavirus s1 Protein, 2019-nCoV, novel coronavirus spike Protein, 2019-nCoV, RBD Protein, 2019-nCoV, S1 Protein, 2019-nCoV |
| 背景说明 | The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4; APN, aminopeptidase N; CEACAM, carcinoembryonic antigen-related cell adhesion molecule 1; Sia, sialic acid; O-ac Sia, O-acetylated sialic acid. The spike is essential for both host specificity and viral infectivity. The term 'peplomer' is typically used to refer to a grouping of heterologous proteins on the virus surface that function together. The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. It's been reported that SARS-CoV-2 (COVID-19 coronavirus, 2019-nCoV) can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. The main functions for the Spike protein are summarized as: Mediate receptor binding and membrane fusion; Defines the range of the hosts and specificity of the virus; Main component to bind with the neutralizing antibody; Key target for vaccine design; Can be transmitted between different hosts through gene recombination or mutation of the receptor binding domain (RBD), leading to a higher mortality rate. |
| 亚细胞定位 | Cytoplasm |
| 免疫原 | Recombinant SARS-CoV-2 / 2019-nCoV Spike/RBD Protein |
| EC | |
| 纯化方法 | Protein A & Antigen Affinity |
| 储存液 | 0.2 μm filtered solution in PBS |
| 储存条件 | Store at -20℃. Avoid freeze/thaw cycles. |
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验. A rabbit polyclonal antisera is also available (101c500; BAbCO) but in our hands this was less reactive. The antibody cleanup protocol is now a seperate document Protocol Cells are grown in 5 mls of YPAD to an O.D. 600 of 0.75 to 1.
suspended in PBS. A rabbit polyclonal antisera is also available (101c500; BAbCO) but in our hands this was less reactive. The antibody cleanup protocol is now a seperate document Protocol Cells are grown in 5 mls of YPAD to an O.D. 600
中科院高福院士课题组 2020 年发表了哪些重要的研究成果？
动物）的 ACE2 可以与 SARS-CoV-2 受体结合域（RBD）并促进 SARS-CoV-2 假病毒的转导。与 SARS-CoV-2 相比，SARS-CoV 似乎在选择受体方面有稍宽的范围。研究进一步以 3Å 分辨率解析了猫 ACE2（cACE2）与 SARS-CoV-2 RBD 的复合体的低温电子显微镜（cryo-EM）结构，揭示了与 hACE2 类似的结合模式与 SARS-CoV- 2 RBD。这些结果为寻找 SARS-CoV-2 的中间宿主提供了亮点，并强调了监控易感宿主以防止进一步爆发的必要
技术资料暂无技术资料 索取技术资料
