K111125P Anti-CDK11A/CDK11B Po

【抗体靶点简介】

Cyclin-dependent kinases (CDKs) are a family of protein kinases first discovered for their role in regulating the cell cycle. They are also involved in regulating transcription， mRNA processing， and the differentiation of nerve cells. They are present in all known eukaryotes， and their regulatory function in the cell cycle has been evolutionarily conserved. CDKs are relatively small proteins， with molecular weights ranging from 34 to 40 kDa， and contain little more than the kinase domain. By definition， a CDK binds a regulatory protein called a cyclin. Without cyclin， CDK has little kinase activity; only the cyclin-CDK complex is an active kinase. CDKs phosphorylate their substrates on serines and threonines， so they are serine-threonine kinases.

【实验操作视频参考】

Western blot实验参考操作流程

Immunohistochemistry实验参考操作流程

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