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文献和实验CD80 分子 CD80 常用单克隆抗体或代号： B7- 1,BB1 主要表达细胞： Ba,Mac,TStr [B] 分子质量(kDa)和结构： gp60(IgSF) 功 能： 活化B细胞抗原,CD28、CTLA- 4配体,提供T细胞共刺激信号 CD80 Aka B7-1, BB1 Ligand for T cell marker CD28 or CTLA4 (CD152
Generation of Antibody Molecules Through Antibody Engineering
been overcome to a large extent using genetic-engineering techniques to produce chimeric mouse/human and completely human antibodies. Such an approach is particularly suitable because of the domain structure of the antibody molecule ( 2 ), where functional
Non-Replicating Recombinant Vaccinia Virus Expressing CD80 to Enhance T-Cell Stimulation
The following method describes the generation of a recombinant vaccinia virus expressing a costimulatory molecule (human CD80 or B7.1). The procedure first requires the cloning, by classical methods not described here, of the gene
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