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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
瓶身
- 保质期:
coa
- 英文名:
SIGMA
- 库存:
999
- 供应商:
麦格生物
- CAS号:
244240-24-2
- 规格:
L6920-5mg
说明
生化/生理作用
LFM-A13 is an inhibitor of the nonreceptor tyrosine kinase Bruton′s tyrosine kinase (Btk), a new molecular target for treatment of B-cell lymphoma and autoimmune disorders. LFMA13 inhibited recombinant BTK with an IC50 value of 2.5microM with 100-fold lower inhibitory activity against a number of other protein kinases including JAK1, JAK2, EGFR, IRK, IKK, and CDK1, 2 and 3, as well as several other related kinases
特点和优势
This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

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文献和实验Negative Regulation of Tec Kinase Alleviates LPS-Induced Acute Kidney Injury in Mice via theTLR4/NF-κB Signaling Pathway.
Wei Zhang et al.
BioMed research international, 2020, 3152043-3152043 (2020-07-21)
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