- ￥3681
- SIGMA
- 美国
- I6909-500UG
- 2025年07月14日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
−20°C
- 保质期：
/
- 英文名：
SIGMA
- 库存：
999
- 供应商：
麦格生物
- 规格：
500UG
说明
免疫原
purified, E. coli-derived recombinant human interleukin-2.
生化/生理作用
Interleukin-2 (IL-2) is a cytokine produced by activated T cells in response to antigen stimulation. IL-2 is important for proliferation of lymphocytes, natural killer cells and macrophages and in the differentiation of CD4+ cells into Th1 and Th2 effector cells. The effects of IL-2 are mediated by the signaling activated by its binding to IL-2 receptor (IL-2 R). IL-2 activates key signaling pathways such as MAPK, JAK/STAT as well as PI3K/Akt. Activation of these pathways modulates production of inflammatory cytokines, survival and progression through cell cycle.
外形
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing carbohydrates.
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文献和实验IL-2 induces a competitive survival advantage in T lymphocytes.
Hans Dooms et al.
Journal of immunology (Baltimore, Md. : 1950), 172(10), 5973-5979 (2004-05-07)
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