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文献和实验Shiga Toxin B-Subunit as a Tool to Study Retrograde Transport
Shiga toxin, produced by Shigella dysenteriae and Shiga toxin-producing Escherichia coli , is a bacterial protein toxin composed of two subunits, A and B (1 ). The A-subunit is the actual toxin whose ribosomal RNA N -glycosidase activity
Methods for the Identification of Host Receptors for Shiga Toxin
The Shiga toxin receptor glycolipid Gb3 (globotriaosylceramide) is also known as the pk blood group antigen (1 ) and as CD77, a germinal center B-cell differentiation antigen (2 ). Tissue localization of Gb3 is associated with sites of Stx
Protocols to Study Effects of Shiga Toxin on Mononuclear Leukocytes
Endothelial cells are regarded as the main targets of the Shiga toxins (Stxs) during infections caused by Stx-producing Escherichia coli (STEC). However, several investigations also confirmed an effect of these toxins on immune cell functions
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