InVivoMAb anti-mouse CD80 (B7-

CD80分子

CD80 分子   CD80 常用单克隆抗体或代号： B7- 1,BB1 主要表达细胞： Ba,Mac,TStr [B] 分子质量(kDa)和结构： gp60(IgSF) 功    能： 活化B细胞抗原,CD28、CTLA- 4配体,提供T细胞共刺激信号   CD80 Aka B7-1, BB1 Ligand for T cell marker CD28 or CTLA4 (CD152

Stimulation of Anti-HIV-1 Cytotoxic T Lymphocytes by Dendritic Cells

molecules CD40, CD80, and CD86 (5 ,6 ), and production of cytokines such as interleukin-12 (IL-12) (7 -9 ), IL-6 (10 ), and interferon α (IFN-α) (10 ,11 ). Moreover, DC can process antigens in various forms by different pathways and induce high levels

CD86分子

, while the second is provided by the B-cell activation antigens B7-1, or CD80 and B7-2, or CD86 by interaction with the T-cell surface molecules CD28 and CTLA4 Positive staining (normal): interdigitating dendritic cells in T zones of secondary lymphoid organs