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- 详细信息
- 文献和实验
- 技术资料
- 亚型:
IgG
- 形态:
液体
- 保存条件:
-20℃
- 克隆性:
多克隆
- 标记物:
无
- 适应物种:
HMR
- 抗原来源:
兔
- 供应商:
万类生物
- 宿主:
兔
- 应用范围:
WB
- 抗体英文名:
UCP2 antibody
- 规格:
50μl(>50μg)
产品概述
UCP2 (uncoupling protein 2) is a member of the mitochondrial carrier protein super family located in the mitochondrial inner membrane. UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells.
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文献和实验Detection of Uncoupling Protein-2 (UCP2) As a Mitochondrial Modulator of Apoptosis
There is an increasing evidence that uncoupling protein-2 (UCP2), a recently identified molecular sensor and suppressor of mitochondrial reactive oxygen species (ROS), plays an important role in �regulating apoptosis in different cell systems
【进展|热点】Nature:线粒体UCP2介导巨噬细胞吞噬功能---细胞吞噬新机制
生物通 报道:来自美国弗吉尼亚州立大学,斯坦福—伯纳姆医学研究所(Sanford-Burnham Medical Research Institute)发现了吞噬细胞线粒体膜蛋白Ucp2在细胞吞噬中的重要作用,这对于解释为什么吞噬细胞能接连消化多个凋亡细胞,而不影响其自身活动具有重要意义。这一研究成果公布在Nature杂志上。 成人每天能产生大量的凋亡细胞,比如大脑中的神经元,能存活下来的并不多,大部分都被吞噬细胞清除了,但是当吞噬细胞清楚死亡细胞的时候,它实质上使其细胞内容增加了一倍
UCP1 orthologues and paralogues (UCP2, UCP3, plant UCP), comparative functional studies require a system with identical mitochondrial, cellular, and genetic backgrounds. In this chapter, the protocols for the ectopic expression of mouse UCP
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