- ￥1200
- 万类生物
- 中国
- WL02373
- 2026年04月26日
- WB
- 兔
- HMR
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- 详细信息
- 文献和实验
- 技术资料
- 亚型：
IgG
- 形态：
液体
- 保存条件：
-20℃
- 克隆性：
多克隆
- 标记物：
无
- 适应物种：
HMR
- 保质期：
一年
- 抗原来源：
兔
- 供应商：
万类生物
- 宿主：
兔
- 应用范围：
WB
- 浓度：
>1 mg/ml
- 靶点：
CDK1/CDC2
- 抗体英文名：
CDK1/CDC2 antibody
- 抗体名：
CDK1/CDC2 抗体
- 规格：
50μl(>50μg)
产品概述
In vertebrates, as in yeast, multiple cyclins have been identified, including a total of eight such regulatory proteins in mammals. In contrast to the situation in yeast, the Cdc2 p34 kinase is not the only catalytic subunit identified in vertebrates that can interact with cyclins. While Cdc2 p34 is essential for the G2 to M transition in vertebrate cells, a second Cdc2-related kinase has also been implicated in cell cycle control. This protein, designated cyclin-dependent kinase 2 (Cdk2) p33, also binds to cyclins and its kinase activity is temporally regulated during the cell cycle. Several additional Cdc2 p34-related cyclin dependent kinases have been identified. These include Cdk3-Cdk8, PCTAIRE-1-3 and KKIALRE.
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文献和实验Assays for Cyclin-Dependent Kinase Inhibitors
several substrates including Rb. On the other hand, CDK2/cyclin A complex is active throughout S phase. For cells to progress to mitosis, CDK1 (CDC2) must be “activated,” and activated cdc2 phosphorylates substrates required for mitosis (3 ).
三句话读懂一篇 CNS：咖啡竟可降低心律失常风险；转入肥胖基
（冷冻电镜技术），打破蛋白纯化等技术瓶颈，首次解析了 ATP 结合状态下的抑制型 AMPK 复合物的高分辨率结构，从结构生物学角度阐述了 AMPK 的活性调节机制，提出了 AMPK 激活、失活、再激活的循环通路模型！图 3：来源 Science4. STM：间质细胞在肠道免疫中的作用炎症性肠病增加了结直肠肿瘤的患病风险。2021 年 7 月 21 日，上海交通大学 Bio-X 研究院李保界教授等团队在 Science Translational Medicine 杂志上发表研究
Analysis of Cyclin-Dependent Kinase Activity
of the cell cycle that require their kinase abilities—CDKs 3, 4, and 6 are active during G1 phase, CDK2 functions during the G1-to-S transition and S phase, and cdc2 (also known as cdk1) is essential for the G2-to-mitosis transition ( 3 ). In vivo
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