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- 详细信息
- 文献和实验
- 技术资料
- 抗体名:
CXCL12/SDF1 Polyclonal Antibody_货号:E-AB-40578_多克隆抗体
- 抗体英文名:
CXCL12/SDF1 Polyclonal Antibody
- 应用范围:
WB
- 宿主:
Rabbit
- 适应物种:
Human;Mouse;Rat
- 保质期:
12个月
- 目录编号:
E-AB-40578
- 级别:
科研级别
- 库存:
999
- 供应商:
武汉伊莱瑞特生物科技股份有限公司
- 标记物:
Unconjugated
- 克隆性:
Polyclonal
- 保存条件:
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
- 形态:
液体
- 亚型:
IgG
- 规格:
200μL/100μL/50μL/20μL
| 规格: | 200μL | 产品价格: | ¥2365.0 |
|---|---|---|---|
| 规格: | 100μL | 产品价格: | ¥1640.0 |
| 规格: | 50μL | 产品价格: | ¥1010.0 |
| 规格: | 20μL | 产品价格: | ¥420.0 |
货号:E-AB-40578
| Verified Samples |
Verified Samples in WB:THP-1,Raw264.7,Rat testis
|
| Dilution |
WB: 1:2000-4000
|
| Clonality |
Polyclonal
|
| Isotype |
IgG
|
| Immunogen |
Recombinant Rat CXCL12 protein expressed by E.coli.
|
| Abbre |
CXCL12
|
| Synonyms |
Cxcl12; SDF-1抗体
|
| Swissprot |
Q9QZD1
|
| Calculated MW |
10kDa
|
| Observed MW |
10kDa
|
| Cellular Localization |
Secreted
|
| Concentration |
1mg/mL
|
| Storage |
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
|
| Buffer |
PBS with 0.02% sodium azide, 50% glycerol,pH 7.4
|
| Purification Method |
Antigen Affinity Purification
|
| Research Areas |
Immunology;Microbiology;Cardiovascular
|
| Conjugation |
Unconjugated
|
| Background |
The stromal cell derived factor 1 (SDF1/CXCL12) is a small, pro-inflammatory chemoattractant cytokine that regulates leukocyte trafficking through interactions with its cognate 7-transmembrane G protein-coupled receptors. The SDF1/CXCL12 receptor, CXCR4, also serves as a coreceptor for the entry of human immunodeficiency virus into target cells. SDF1/CXCL12 may regulate homing and maintenance of CXCR4-expressing stem or progenitor cells, including embryonic and many somatic stem cells. Many cancer cells express CXCR4, suggesting that SDF1/CXCL12 plays a role in cancer metastasis. Alternative splicing and differential processing during maturation produce a pair of SDF1/CXCL12 isoforms (SDF1/CXCL12α and SDF1/CXCL12β) that have different properties and biological activities. Additional isoforms of SDF1/CXCL12 have been reported.
|
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