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Anti-BAZ2A Polyclonal Antibody

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  • ¥960 - 1600
  • Solarbio已认证
  • K112925P
  • 北京
  • 2025年07月13日
  • WB
  • Rabbit
  • Human;Mouse
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 抗体名

      bromodomain adjacent to zinc finger domain protein 2A;bromodomain adjacent to zinc finger domain, 2A;DKFZp781B109;FLJ45876;hWALp3;KIAA0314FLJ13768;Tip5;TIP5FLJ13780;Transcription termination factor I-interacting protein 5;TTF-I interacting peptide 5;TTF-I-interacting protein 5;WALp3;

    • 抗体英文名

      Anti-BAZ2A Polyclonal Antibody

    • 靶点

      BAZ2A

    • 浓度

      WB 1:1000-3000.

    • 应用范围

      WB

    • 宿主

      Rabbit

    • 适应物种

      Human;Mouse

    • 保质期

      1-3年

    • 抗原来源

      A synthetic peptide of human BAZ2A

    • 目录编号

      11176

    • 级别

      科研级别

    • 库存

      999

    • 供应商

      北京索莱宝科技有限公司

    • 标记物

      Biotin,Cy3,Cy3.5,Cy5,Cy5.5,Cy7,FITC,HRP,RBITC,SAlexa Fluor 350,SAlexa Fluor 405,SAlexa Fluor 488,SAlexa Fluor 532,SAlexa Fluor 555,SAlexa Fluor 568,SAlexa Fluor 594,SAlexa Fluor 633,SAlexa Fluor 640,SAlexa Fluor 647,SAlexa Fluor 660,SAlexa Fluor 680,SAlexa Fluor 750

    • 克隆性

      多克隆

    • 保存条件

      Store at -20℃. Avoid freeze / thaw cycles.

    • 形态

      液体/冻干粉

    • 亚型

      IgG

    • 免疫原

      A synthetic peptide of human BAZ2A

    • 规格

      50ul/100ul

    规格:50ul产品价格:¥960.0
    规格:100ul产品价格:¥1600.0

     

    Regulatory subunit of the ATP-dependent NoRC-1 and NoRC-5 ISWI chromatin remodeling complexes, which form ordered nucleosome arrays on chromatin and facilitate access to DNA during DNA-templated processes such as DNA replication, transcription, and repair. Both complexes regulate the spacing of nucleosomes along the chromatin and have the ability to slide mononucleosomes to the center of a DNA template. Directly stimulates the ATPase activity of SMARCA5 in the NoRC-5 ISWI chromatin remodeling complex. The NoRC-1 ISWI chromatin remodeling complex has a lower ATP hydrolysis rate than the NoRC-5 ISWI chromatin remodeling complex. Within the NoRC-5 ISWI chromatin remodeling complex, mediates silencing of a fraction of rDNA by recruiting histone-modifying enzymes and DNA methyltransferases, leading to heterochromatin formation and transcriptional silencing (By similarity. In the complex, it plays a central role by being recruited to rDNA and by targeting chromatin modifying enzymes such as HDAC1, leading to repress RNA polymerase I transcription (By similarity. Recruited to rDNA via its interaction with TTF1 and its ability to recognize and bind histone H4 acetylated on 'Lys-16' (H4K16ac, leading to deacetylation of H4K5ac, H4K8ac, H4K12ac but not H4K16ac (By similarity. Specifically binds pRNAs, 150-250 nucleotide RNAs that are complementary in sequence to the rDNA promoter; pRNA-binding is required for heterochromatin formation and rDNA silencing (By similarity.

    产品细节图片1
    Western blot analysis with BAZ2A antibody diluted at 1:2000;Lane: MDA-MB-231,PC-3M-IE8.

     

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    图标文献和实验
    相关实验
    • Polyclonal Antibody Production

      , if desired this is best accomplished by Protein A Affinity Chromatography.   上一篇:make an Antibody against a Peptides   下一篇:Immunization Protocol for Monoclonal Antibody Production

    • Polyclonal Antibody Production

        Polyclonal Antibody Production Very useful for rapid and simple generation of antibodies for western blots, ELISA assays, and immunoprecipitation.     Rabbit Immunization Initial Preparation Your antigen

    • Human Anti-antibody Response

      a simple ELISA method to detect human anti-antibody response.

    图标技术资料

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