- ￥960
- Solarbio
- K112252P-50ul
- 北京
- 2025年12月22日
- IHC
- Rabbit
- Human;Mouse;Rat
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- 详细信息
- 文献和实验
- 技术资料
- 靶点：
TIPRL
- 应用范围：
IHC
- 宿主：
Rabbit
- 适应物种：
Human;Mouse;Rat
- 保质期：
一年
- 供应商：
北京索莱宝科技有限公司
- 克隆性：
Polyclonal Antibody
- 保存条件：
Store at -20℃. Avoid freeze / thaw cycles.
- 亚型：
IgG
- 免疫原：
Recombinant protein of human TIPRL
- 规格：
50ul
| 中文名称 | TIP41, TOR信号通路调节样蛋白抗体 |
| 靶标 | TIPRL |
| 别名 | 1810011K17Rik; dJ69E11.3; MGC3794; Putative MAPK activating protein PM10; Putative MAPK-activating protein PM10; RP1-69E11.1; Tip; TIP41; TIP41-like protein; tiprl; TIPRL_HUMAN; TOR Signaling Pathway Regulator like; Type 2A-interacting protein |
| 背景资料 | May be a allosteric regulator of serine/threonine-protein phosphatase 2A (PP2A). Isoform 1 inhibits catalytic activity of the PP2A(D) core complex in vitro. The PP2A(C):TIPRL complex does not show phosphatase activity. Acts as negative regulator of serine/threonine-protein phosphatase 4 probably by inhibiting the formation of the active PPP4C:PPP4R2 complex; the function is proposed to implicate it in DNA damage response by promoting H2AX phosphorylated on Ser-140 (gamma-H2AX). May play a role in the regulation of ATM/ATR signaling pathway controlling DNA replication and repair. |
| Swiss Prot | O75663 |
| Gene ID | 261726 |
| 亚细胞定位 | Cytoplasm |
| 宿主 | Rabbit |
| 克隆类型 | Polyclonal Antibody |
| 亚型 | IgG |
| 蛋白分子量 | 20/31kDa |
| 稀释比例 | IHC 1:50-200. |
| 免疫原 | Recombinant protein of human TIPRL |
| Public Immunogen Range | 1-179aa |
| 纯化方法 | Affinity purification |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 保存 | Store at -20℃. Avoid freeze / thaw cycles. |
| 交叉反应 | Human;Mouse;Rat |
| 应用 | IHC |
| 规格 | 50ul 100ul |
| 单位 | 支 |
备注：
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these methods.
实验图
Immunohistochemistry of paraffin-embedded human colorectal cancer with TIPRL antibody diluted at 1:100.
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文献和实验Polyclonal Antibody Production
, if desired this is best accomplished by Protein A Affinity Chromatography. 上一篇：make an Antibody against a Peptides 下一篇：Immunization Protocol for Monoclonal Antibody Production
Polyclonal Antibody Production
Polyclonal Antibody Production Very useful for rapid and simple generation of antibodies for western blots, ELISA assays, and immunoprecipitation. Rabbit Immunization Initial Preparation Your antigen
a simple ELISA method to detect human anti-antibody response.
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