supernatant weredetected. The morphology, viability, apoptosis,andcaspase-3activityofH9C2cells wereexam-inedbyHEstaining,MTTmethod,flowcytometry,andcolorimetry,respectively.Westernblottingwasusedtodetect the expression ofcaspase3 and HMGB1/RAGE/NF-κB pathwayproteins.Results:Comparedwiththecon- trolgroup,the
LeeSS, CheahYK.TheInterplaybetweenMicroRNAsand and mephylation of histones H3 and H4 are the most frequent and well-characterized histone modifications and may be associated with disease severity parameters and serve as therapeutic response markers. Many specific microRNAs dysregulated in non-tumor dermatological disease have been reviewed. Deepening the study of how epigenetic mechanisms influence non-tumor
supernatant weredetected. The morphology, viability, apoptosis,andcaspase-3activityofH9C2cells wereexam-inedbyHEstaining,MTTmethod,flowcytometry,andcolorimetry,respectively.Westernblottingwasusedtodetect the expression ofcaspase3 and HMGB1/RAGE/NF-κB pathwayproteins.Results:Comparedwiththecon- trolgroup,the