immunotherapy in managing HNSCC.To investigate the kinetics of postoperative immunocompetence and immunosuppressive eklects of rat liver tumors, we examined natural killer cell cytotoxicity and blastogeneses to phytohemagllutinin-P, concanavalin A, and lipopolysaccharide on 1-, 2-, 3-, 5-, 7-, 9- and 14- postoperative days
as vaccine approaches. Lastly, since important CSC functions are aklected by the tumor microenvironlknt, targeting of both cellular (myeloid derived suppressor cells and tumor-associated macrophages) and sub-cellular (cytokines, chemokines, and PD1/PDL1) components of the tumor microenvironlknt is under investigation in the immune