- 询价
- MedChemExpress(MCE)
- HY-111375
- 美国
- 2026年05月26日
企业认证
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 库存：
999
- 英文名：
Azoxymethane
- CAS号：
25843-45-2
- 保质期：
见包装
- 供应商：
北京智杰方远科技有限公司
- 保存条件：
-20°C储存
- 规格：
询价
Azoxymethane is a colon carcinogen which leads to the formation of DNA adducts. On an equal protein basis, hepatic microsomes are much more active than SI and colon microsomes in NADPH-dependent Azoxymethane bioactivation and N7-mG adduct formation. Hepatic microsomes show the highest activity in the hydroxylation of Azoxymethane, followed by SI and colon microsomes
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Regardless of the strain, the amounts of O6-mG and N7-mG produced by Azoxymethane are highest in the liver, followed by proximal and distal colons, which have similar levels, and then by duodenum, jejunum and ileum. Results indicate that the Azoxymethane-induced DNA adduct formation in the SI and colon does not depend on bioactivation by hepatic P450 enzymes. Irrespective of the mouse strain, no aberrant crypt foci (ACF) is detected in the colons of saline-treated mice; in contrast, colonic ACF is detected in all three strains of Azoxymethane-treated mice. The Azoxymethane-treated athymic mice have approximately an 11-fold lower tumor incidence than similarly treated WT animals.
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验Section.03 小结 好啦，今天关于肿瘤标志物就先介绍到这里了~MCE 提供大量肿瘤标志物抗体，快来 MCE 官网挑选你心仪的抗体吧!点击直达官网。 小伙伴还需要注意：每一个肿瘤标志物，都不是孤立的“判决书”，一定要结合多种检测指标联合判断，才能更准确。 产品推荐 PD-L1 Antibody (YA4674) (HY-P84982) www.medchemexpress.cn/antibody/cd274-pd
-antibody-ya1099.html 可用于卵巢癌组织的免疫组化分析 PAX8 Antidiv (YA5894) (HY-P86202) www.medchemexpress.cn/antibody/pax-8-antibody-ya5894.html 可用于卵巢癌组织的免疫组化分析 注：内容不全，MCE 公众号原文参考：mp.weixin.qq.com/s/o2TXkM2jVVKMvFXlewReug 参考文献 [1] 黄蕊，等. 类器官技术在中医药领域的应用
的靶点分布呈现出明显集中的特点，主要集中在少数几个关键的激酶家族上[19]。 表3. 获批激酶抑制剂的靶点分布[19]。 总的来说，已获批激酶抑制剂的靶点分布高度集中于驱动癌症和自身免疫性疾病的关键信号通路上，尤其是酪氨酸激酶家族。 MCE 相关产品 一、主要激酶家族的重组蛋白:含常见突变体如 EGFR L858R/T790M/C797S（www
技术资料暂无技术资料 索取技术资料
