- ￥398
- 戴格
- 浙江杭州
- db11925
- 2026年02月03日
- WB, IHC-P, ICC/IF, FC, IP
- Rabbit
- Human,Mouse,Rat
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- 详细信息
- 技术资料
- 免疫原：
A synthetic peptide of human Thymidylate Synthase
- 亚型：
IgG
- 保存条件：
Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
- 克隆性：
Monoclonal
- 适应物种：
Human,Mouse,Rat
- 库存：
99
- 宿主：
Rabbit
- 应用范围：
WB, IHC-P, ICC/IF, FC, IP
- 靶点：
Thymidylate Synthase
- 规格：
10μl
Thymidylate synthase catalyzes the methylation of deoxyuridylate to deoxythymidylate using, 10-methylenetetrahydrofolate (methylene-THF) as a cofactor. This function maintains the dTMP (thymidine-5-prime monophosphate) pool critical for DNA replication and repair. The enzyme has been of interest as a target for cancer chemotherapeutic agents. It is considered to be the primary site of action for 5-fluorouracil, 5-fluoro-2-prime-deoxyuridine, and some folate analogs. Expression of this gene and that of a naturally occurring antisense transcript, mitochondrial enolase superfamily member 1 (GeneID:55556), vary inversely when cell-growth progresses from late-log to plateau phase. Polymorphisms in this gene may be associated with etiology of neoplasia, including breast cancer, and response to chemotherapy. [provided by RefSeq, Aug 2017]
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技术资料暂无技术资料 索取技术资料
Thymidylate Synthase (DGR13401) Rabbit mAb
￥398
