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FOXP3 Mouse (7H9) mAb

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  • ¥1400 - 2400
  • 戴格
  • db6076
  • 2026年01月30日
  • WB,ICC/IF
  • Mouse
  • Transfected
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 保存条件

      Store at -20°C. Supplied in PBS, 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. Stable for 12 months from date of receipt.

    • 适应物种

      Transfected

    • 保质期

      12个月

    • 库存

      现货

    • 宿主

      Mouse

    • 应用范围

      WB,ICC/IF

    • 靶点

      FOXP3 Mouse

    • 规格

      50μL/100μL

    规格:50μL产品价格:¥1400.0
    规格:100μL产品价格:¥2400.0
    Defects in FOXP3 are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) [MIM/304790]; also known as X-linked autoimmunity-immunodeficiency syndrome. IPEX is characterized by neonatal onset insulin-dependent diabetes mellitus, infections, secretory diarrhea, trombocytopenia, anemia and eczema. It is usually lethal in infancy..

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    图标文献和实验
    相关实验
    • Purification of mAb (IgG)

      (adjust pH to 7.8 with Binding buffer; red color) to the Protein A column.Mouse antibodies of the IgG1 subclass do not have a high affinity for protein A. Purification on protein A beads using standard conditions will yield approximately 1/10

    • In Vivo Depletion of FoxP3+ Tregs Using the DEREG Mouse Model

      was precluded due to the lack of appropriate markers. Only after the discovery of Foxp3 as a Treg-specific transcription factor, was the development of Treg-specific mouse models feasible. We generated DEREG mice (DEpletion of REGulatory T cells), a BAC

    • ChIP-on-Chip for FoxP3

      . Mice and human with Foxp3 mutations are severely impaired in Treg cell generation and develop lethal autoimmune diseases. We combined chromatin immuno-precipitation and mouse whole genome tiling array profiling (ChIP-on-Chip) to identify the direct

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