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CDK4 (3F9) Mouse mAb

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  • ¥1400 - 2400
  • 戴格
  • db6087
  • 2025年11月23日
  • WB
  • Mouse
  • Human, Mouse, Rat
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  • 企业认证

    • 详细信息
    • 文献和实验
    • 技术资料
    • 保存条件

      Store at -20°C. Supplied in PBS, 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. Stable for 12 months from date of receipt.

    • 适应物种

      Human, Mouse, Rat

    • 保质期

      12个月

    • 库存

      现货

    • 宿主

      Mouse

    • 应用范围

      WB

    • 靶点

      CDK4

    • 规格

      50μL/100μL

    规格:50μL产品价格:¥1400.0
    规格:100μL产品价格:¥2400.0
    Ser/Thr-kinase component of cyclin D-CDK4 (DC) complexes that phosphorylate and inhibit members of the retinoblastoma (RB) protein family including RB1 and regulate the cell-cycle during G1/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complexes and the subsequent transcription of E2F target genes which are responsible for the progression through the G1 phase. Hypophosphorylates RB1 in early G1 phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. Also phosphorylates SMAD3 in a cell-cycle-dependent manner and represses its transcriptional activity. Component of the ternary complex, cyclin D/CDK4/CDKN1B, required for nuclear translocation and activity of the cyclin D-CDK4 complex.

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    图标文献和实验
    相关实验
    • Purification of mAb (IgG)

      (adjust pH to 7.8 with Binding buffer; red color) to the Protein A column.Mouse antibodies of the IgG1 subclass do not have a high affinity for protein A. Purification on protein A beads using standard conditions will yield approximately 1/10

    • Purification of mAb (IgG)

        Purification of mAb (IgG) by Chang-Duk Jun, 03/14/2000 Purpose Materials Antibody 7E3 , 2L sup grown in flasks, frozen and thawed overnight. BioRad Affi-Gel Protein A MAPS II Buffers

    • T-Cell Activation Using mAb to CD3

      One of the most common ways to assess T cell activation is to measure T cell proliferation upon in vitro stimulation of T cells via antigen or agonistic antibodies to TCR. This protocol is written as a starting point for examining in vitro proliferation of mouse

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    CDK4 (3F9) Mouse mAb
    ¥1400 - 2400