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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
A synthetic peptide of human NF-kB p65
- 亚型:
IgG
- 保存条件:
Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
- 克隆性:
Monoclonal
- 适应物种:
Human, Mouse, Rat
- 库存:
99
- 宿主:
Rabbit
- 应用范围:
WB, ICC/IF, FC
- 靶点:
NF-kB p65
- 规格:
10μl
NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
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文献和实验相关实验
下沙 各位战友,关于NF-kB的激活,我查了一些资料,有人认为通过western研究P65的表达量可以反映NF-kB的激活。因为P65的磷酸化和IkB的磷酸化可以反映NF-kB的激活,我比较困惑的是到底采用western检测P65、磷酸化P65还是IkB呢?是检测胞浆中的蛋白吗?如果是检测P65,NF-kB激活时,P65是升高还是降低呢?谢谢! magichunter 1、提取细胞全蛋白,然后测定磷酸化的P65表达,如果表达
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NF-kB p65 (DGR19469) Rabbit mAb
¥398







