- ￥850 - 2400
- 戴格
- db12896
- 2026年01月02日
- WB,IHC,ICC/IF,FC,IP
- Rabbit
- Human
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
- 适应物种：
Human
- 保质期：
12个月
- 库存：
现货
- 宿主：
Rabbit
- 应用范围：
WB,IHC,ICC/IF,FC,IP
- 靶点：
STAT3
- 规格：
20μL/50μL/100μL
| 规格： | 20μL | 产品价格： | ￥850.0 |
|---|---|---|---|
| 规格： | 50μL | 产品价格： | ￥1400.0 |
| 规格： | 100μL | 产品价格： | ￥2400.0 |
The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. Mutations in this gene are associated with infantile-onset multisystem autoimmune disease and hyper-immunoglobulin E syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Sep 2015]
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文献和实验Efficient Liposome-Mediated Gene Transfer to Rabbit Carotid Arteries In Vivo
Methods for gene delivery in vivo vary dramatically in their relative efficiencies. The most efficient to date involve the use of recombinant viruses, most notably adenoviruses, adeno-associated viruses (AAVs), or retroviruses (see Chapters
Recombinant Immunotoxins in the Treatment of Cancer
Recombinant immunotoxins are chimeric proteins composed of the Fv portion of a monoclonal antibody (MAb) fused to a portion of a toxin. The Fv replaces the cell-binding domain of the toxin and directs the toxin to cancer cells that express
Expression of Recombinant Antibodies in Mammalian Cell Lines
Since the advent of hybridoma technology, mammalian-cell culture has been employed for the expression and high-level production of monoclonal antibodies (MAbs). Recent adaptations in recombinant technology have developed the use of numerous
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