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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
- 适应物种:
Human
- 保质期:
12个月
- 库存:
现货
- 宿主:
Rabbit
- 应用范围:
WB,IHC,ICC/IF,FC,IP
- 靶点:
E Cadherin
- 规格:
20μL/50μL/100μL
| 规格: | 20μL | 产品价格: | ¥850.0 |
|---|---|---|---|
| 规格: | 50μL | 产品价格: | ¥1400.0 |
| 规格: | 100μL | 产品价格: | ¥2400.0 |
This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function of this gene is thought to contribute to cancer progression by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. This gene is present in a gene cluster with other members of the cadherin family on chromosome 16. [provided by RefSeq, Nov 2015]
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文献和实验Expression and Isolation of Recombinant Antibody Fragments in E. coli
Central to the rapid growth in the study and application of recombinant antibodies in recent years is the ability to reliably and cost-effectively produce large quantities of functional protein. In contrast to glycosylated whole monoclonal
Cadherin-Mediated Cell-Cell Interactions
, intestine Ksp-Cadherin a Rabbit Kidney HPT-1 Cadherin a,b Human
Expression of Eukaryotic Cytochromes P450 in E. coli
Although much has been learned from the study of relatively abundant cytochromes P450 (e.g., P450cam from Pseudomonas putida cytosol, P4501A2 and P4502B4 from rabbit liver microsomes, and P45Oscc from bovine adrenal cortex mitochondria
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