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- MedChemExpress(MCE)
- 美国
- HY-W278944
- 2025年12月05日
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- 保存条件：
4°C, protect from light
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- CAS号：
19819-18-2
- 规格：
25 mg/100 mg
| 规格： | 25 mg | 产品价格： | ￥570.0 |
|---|---|---|---|
| 规格： | 100 mg | 产品价格： | ￥1823.0 |
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Antiproliferative agent-15
CAS No. : 19819-18-2
MCE 国际站：Antiproliferative agent-15
产品活性：Antiproliferative agent-15 是一种抗癌剂， 对人结肠癌细胞系 (HCT116 和 HCT15)、脑癌细胞系 (LN-229 和 GBM-10) 显示出抗增殖活性。
研究领域：Others
作用靶点：Others
In Vitro: Antiproliferative agent-15 (compound 6a) shows antiproliferative activity against human colon (HCT116 and HCT15), brain (LN-229 and GBM-10) cancer cell lines, with IC50 values of 8.3 μM, 4.8 μM, 18.3 μM, and 12 μM, respectively. However, Antiproliferative agent-15 has no active against ovarian (A2780) cancer cell lines and normal cell line (CHO).
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文献和实验One of the more intriguing features of the hemopoietic system is the ability of a single phenotypically homogeneous stem cell to give rise—through differentiation and development—to all the phenotypically diverse mature immuno-hemopoietic
compounds and for the derivation of IC50 values. IC50 value is defined as the concentration of a test compound required to achieve half maximal inhibition of methyl-[3H]-thymidine incorporation, a parameter that is indicative of antiproliferative potency. IC
Functional Analysis of the Antimitogenic Activity of Tumor Suppressors
Loss of tumor suppressors contributes to numerous cancer types. Many, but not all, proteins encoded by tumor suppressor genes have antiproliferative activity and halt cell-cycle progression. In this chapter, we present three methods
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