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- 详细信息
- 技术资料
- 保存条件:
Powder: -20°C, 3 years; 4°C, 2 years. In solvent: -80°C, 6 months; -20°C, 1 month.
- 库存:
货期:1-2天
- 供应商:
MedChemExpress LLC
- CAS号:
2403733-82-2
- 规格:
10 mM * 1 mL/1 mg/5 mg/10 mg
| 规格: | 10 mM * 1 mL | 产品价格: | ¥4551.0 |
|---|---|---|---|
| 规格: | 1 mg | 产品价格: | ¥1600.0 |
| 规格: | 5 mg | 产品价格: | ¥4100.0 |
| 规格: | 10 mg | 产品价格: | ¥6700.0 |
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GLPG3970
CAS No. : 2403733-82-2
MCE 国际站:GLPG3970
产品活性:GLPG3970 (compound 88) 是一类首创的 SIK2/SIK3 抑制剂。GLPG3970 可用于炎症和自身免疫性疾病的研究。
作用靶点:Salt-inducible Kinase (SIK)
In Vivo: GLPG3970 (10 mg/kg; oral administration; twice daily for 5 consecutive days) decreases the ear thickness of murine models of psoriatic-like epidermal hyperplasia induced by intradermal injections of IL-23.
GLPG3970 (60 mg/kg; oral administration; twice daily until mice are sacrificed) shows better clinical manifestations compared to vehicle groups in murine collagen-antibody induced arthritis model (CAIA).
GLPG3970 (30 mg/kg; oral administration; twice daily for 7 consecutive days) reduces disease activity index ompared to vehicle groups in mice T cell transfer model.
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