- ￥10600
- TargetMol
- 美国
- T39771
- 2025年07月09日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
零下80~20°C
- 保质期：
Powder: -20°C for 3 years In solvent: -80°C for 2 years
- 英文名：
nAChR agonist CMPI hydrochloride
- 库存：
10
- 供应商：
TargetMol
- CAS号：
2250025-94-4
- 规格：
25 mg
Product Introduction
Bioactivity
英文名:nAChR agonist CMPI hydrochloride
描述:CMPI hydrochloride, a potent and selective nAChR agonist, functions as a positive allosteric modulator (PAM) specifically targeting the α4:α4 subunit interface of the nAChR. It enhances the response of the (α4)3(β2)2 nAChR to acetylcholine (ACh) (10 μM) with an EC 50 of 0.26 μM. With its potential for researching nicotine dependence and various neuropsychiatric conditions linked to reduced brain cholinergic activity, CMPI hydrochloride stands as a significant compound in neurological research.
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文献和实验and disease. Keywords: agonist; antagonist allosteric modulator; G protein?coupled receptor; heterotrimeric G protein; ion channels; ligand; new chemical entity (NCE); orphan receptor; structure activity relationship (SAR
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