- ￥10600
- TargetMol
- 美国
- T39661
- 2025年07月12日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
零下80~20°C
- 保质期：
Powder: -20°C for 3 years In solvent: -80°C for 2 years
- 英文名：
CCR4 antagonist 3
- 库存：
10
- 供应商：
TargetMol
- CAS号：
2174938-70-4
- 规格：
25 mg
Product Introduction
Bioactivity
英文名:CCR4 antagonist 3
描述:CCR4 antagonist 3 is an orally active, potent and selective CCR4 antagonist. CCR4 antagonist 3, featuring a novel piperidinyl-azetidine motif, has IC 50 s of 22 nM and 50 nM in the calcium flux and CTX assay. CCR4 antagonist 3 has antitumor activity.
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文献和实验Characterization of Chemokine Receptors
a whole‐cell assay. The competition is homologous in that the radiolabeled and unlabeled ligand are both human TARC, which is species cross‐reactive such that it also binds to the murine CCR4 receptor. The IC50 value obtained in this experiment is 0.9 nM
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