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Rabbit anti-NLRP3 Polyclonal A

ntibody,NLRP3抗体
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  • ¥1600
  • 爱必信(absin)
  • abs151715
  • 上海
  • 2025年07月08日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 抗体名

      NLRP3抗体

    • 抗体英文名

      NLRP3,AGTAVPRL,AII,AVP,C1orf7,CIAS1,CLR1.1,FCAS,FCAS1,FCU,MWS,NALP3,PYPAF1

    • 靶点

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    • 浓度

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    • 应用范围

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    • 宿主

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    • 适应物种

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    • 保质期

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    • 抗原来源

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    • 目录编号

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    • 级别

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    • 库存

      现货

    • 供应商

      爱必信(上海)生物科技有限公司

    • 标记物

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    • 克隆性

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    • 保存条件

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    • 形态

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    • 亚型

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    • 免疫原

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    • 规格

      50ul

    别名 NLRP3抗体;NLRP3,AGTAVPRL,AII,AVP,C1orf7,CIAS1,CLR1.1,FCAS,FCAS1,FCU,MWS,NALP3,PYPAF1
    宿主 Rabbit
    反应种属 Human,Mouse,Rat
    应用 WB 1:500 - 1:2000
    IF 1:50 - 1:200
    分子量 Detects a band of approximately 110kD
    Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
    免疫原 Recombinant protein of human NLRP3
    纯化方法 Affinity purification
    类型 Polyclonal Antibody
    同种型 IgG
    存储溶液 Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
    背景说明 This gene encodes a pyrin-like protein containing a pyrin domain, a nucleotide-binding site (NBS) domain, and a leucine-rich repeat (LRR) motif. This protein interacts with the apoptosis-associated speck-like protein PYCARD/ASC, which contains a caspase recruitment domain, and is a member of the NALP3 inflammasome complex. This complex functions as an upstream activator of NF-kappaB signaling, and it plays a role in the regulation of inflammation, the immune response, and apoptosis. Mutations in this gene are associated with familial cold autoinflammatory syndrome (FCAS), Muckle-Wells syndrome (MWS), chronic infantile neurological cutaneous and articular (CINCA) syndrome, and neonatal-onset multisystem inflammatory disease (NOMID). Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. Alternative 5' UTR structures are suggested by available data; however, insufficient evidence is available to determine if all of the represented 5' UTR splice patterns are biologically valid.
    UniProt Q96P20

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    文献支持
    Rabbit anti-NLRP3 Polyclonal Antibody,NLRP3抗体
    ¥1600