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- 详细信息
- 文献和实验
- 技术资料
- 英文名:
,Complement Component C3a, Anaphylatoxin, C3a
- 库存:
99
- 供应商:
爱必信(上海)生物科技有限公司
- 规格:
1mg/500ug/50ug/10ug
| 规格: | 1mg | 产品价格: | ¥18480.0 |
|---|---|---|---|
| 规格: | 500ug | 产品价格: | ¥13583.0 |
| 规格: | 50ug | 产品价格: | ¥2778.0 |
| 规格: | 10ug | 产品价格: | ¥926.0 |
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产品描述: 产品名称:Recombinant Mouse Complement Component C3a/C3a 描述: Recombinant Mouse Complement Component C3a is produced by our E.coli expression system and the target gene encoding Ser671-Arg748 is expressed. 氨基酸序列: SVQLMERRMDKAGQYTDKGLRKCCEDGMRDIPMRYSCQRRARLITQGENCIKAFIDCCNHITKLR EQHRRDHVLGLAR 背景说明: Complement is defined as key part of innate immunity and as the first line of defense in the fight against invading pathogens. Complement 3 (C3) is the most abundant component of the complement cascade and the convergent point for all three major complement activation pathways: namely classical, alternative and mannose-binding lectin pathways. Complement activation leads to the formation of the C3 convertase, which cleaves C3 into the key effector molecules, C3a (anaphylatoxin) and C3b (opsonin) which then drive microbe removal. By binding to C3a receptor (C3aR), C3a exhibits potent anaphylatoxin activity, including increased vascular permeability, triggering degranulation of mast cells, inflammation, and activating leukocytes. 英文别名: Complement Component C3a, Anaphylatoxin, C3a Accession: P01027 中文别名: Complement Component C3a蛋白, C3a蛋白 来源: Escherichia coli. 纯度: Greater than 95% as determined by reducing SDS-PAGE. 内毒素水平: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test. 形态: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. 溶解方法: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
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文献和实验Expression and Purification Methods for the Production of Recombinant Human Complement Component C2
Human complement component C2 is a critical factor of the classical complement pathway. Here we provide a method for the production of recombinant human C2 (rhC2) protein for research purposes. The human complement component C2 (hC
Purification and Characterization of Human and Mouse Complement C3
Complement component C3 is the most abundant complement protein in plasma, central to all three complement activation pathways and essential to complement amplification. Thus, it is one of the most extensively studied complement proteins
Detection of Complement Receptors 1 and 2 on Mouse Splenic B Cells Using Flow Cytometry
for the complement component 3 (C3) cleavage fragments C3d(g) and iC3b. Additionally, CR1 is a receptor for C3b and regulates complement convertase activity. CR1 and CR2 have various functions including antigen retention by FDC, regulation of surface complement
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