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- Elabscience
- 湖北武汉
- E-AB-51039
- 2025年07月12日
- IHC-p
- Mouse
- Human;Mouse;Rat
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- 详细信息
- 文献和实验
- 技术资料
- 亚型：
IgG
- 形态：
液体
- 保存条件：
在-20℃下储存有效期为12个月。 避免冻融循环。
- 克隆性：
Monoclonal
- 标记物：
Unconjugated
- 适应物种：
Human;Mouse;Rat
- 保质期：
12个月
- 目录编号：
E-AB-51039
- 级别：
科研级别
- 库存：
999
- 供应商：
武汉伊莱瑞特生物科技股份有限公司
- 宿主：
Mouse
- 应用范围：
IHC-p
- 抗体英文名：
Phospho-ERK 1/2 (Tyr222/205) Monoclonal Antibody
- 抗体名：
Phospho-ERK 1/2 (Tyr222/205) 单克隆抗体_货号:E-AB-51039_修饰性抗体
- 规格：
120μL/60μL/20μL
| 规格： | 120μL | 产品价格： | ￥2415.0 |
|---|---|---|---|
| 规格： | 60μL | 产品价格： | ￥1510.0 |
| 规格： | 20μL | 产品价格： | ￥630.0 |
Phospho-ERK 1/2 (Tyr222/205) 单克隆抗体产品名称：Phospho-ERK 1/2 (Tyr222/205) 单克隆抗体， 货号：E-AB-51039
| 已验证样本 | 免疫组织化学（IHC）已验证样本:Human colon carcinoma,Human breast carcinoma |
| 稀释 | IHC 1:100-200 |
| 克隆性 | Monoclonal |
| 同种型 | IgG |
| 免疫原 | Synthetic Peptide of Phospho-ERK 1/2 (Tyr222/205) |
| Abbre | Phospho-ERK 1/2 (Tyr222/205) |
| 同义词 | MAPK3;ERK1;PRKM3;Mitogen-activated protein kinase 3;MAP kinase 3;MAPK 3;ERT2;Extracellular signal-regulated kinase 1;ERK-1;Insulin-stimulated MAP2 kinase;MAP kinase isoform p44;p44-MAPK;Microtubule-associated protein 2 kinase;p抗体 |
| Swissprot | P27361,P28482 |
| 细胞定位 | Nucleus. |
| 浓度 | 1mg/mL |
| 储存方法 | 在-20℃下储存有效期为12个月。 避免冻融循环。 |
| 缓冲 | PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4 |
| 纯化方法 | Protein A purification |
| 研究领域 | Cancer;Signal Transduction;Neuroscience |
| Clone No. | Clone:4D4 |
| Conjugation | Unconjugated |
| 产品描述： | Involved in both the initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors such as ELK1. Phosphorylates EIF4EBP1; required for initiation of translation. Phosphorylates microtubule-associated protein 2 (MAP2). Phosphorylates SPZ1 (By similarity). Phosphorylates heat shock factor protein 4 (HSF4) and ARHGEF2.Acts as a transcriptional repressor. Binds to a [GC]AAA[GC] consensus sequence. Repress the expression of interferon gamma-induced genes. Seems to bind to the promoter of CCL5, DMP1, IFIH1, IFITM1, IRF7, IRF9, LAMP3, OAS1, OAS2, OAS3 and STAT1. Transcriptional activity is independent of kinase activity. |
Phospho-ERK 1/2 (Tyr222/205) 单克隆抗体labscience®拥有先进的单抗，多抗和流式抗体开发技术平台，提供8500+高品质 抗体， 适用于胞内和胞外蛋白的鉴定、定量和定位研究。抗体已在多种应用中得到验证，包含 流式细胞术（Flow Cytometry）、 免疫印迹（WB）、 免疫组化（IHC/ICC）、 免疫（共）沉淀（IP/Co-IP）、 免疫荧光（IF） 等实验。抗体产品涉及多种生命科学研究领域，包括肿瘤、免疫、心血管、细胞生物学、神经科学、表观遗传学等。Elabscience®始终致力于提高抗体的质量和种类，以保障并加快您的研究进程
在-20℃下储存有效期为12个月。 避免冻融循环。Phospho-ERK 1/2 (Tyr222/205) 单克隆抗体产品更多产品信息查看欢迎咨询我们和搜索武汉伊莱瑞特Elabscience官网查看。
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文献和实验Using Phospho‐Motif Antibodies to Determine Kinase Substrates
the phosphorylation site; therefore, substrate?directed, phosphorylation?state?sensitive, motif?specific (?phospho?motif?) antibodies represent powerful tools to identify novel kinase substrates and to investigate mechanisms of substrate phosphorylation
) is accompanied with or inactivates the GSK activity. However, it is still not conclusive what the role of Tyr phosphorylation (Y216 fro beta, Y279 for alpha) on GSK activity is. One reference is a review paper published in Cell in 2001, you may take a quick
Using the scan‐x Web Site to Predict Protein Post‐Translational Modifications
spectrometry data is providing evidence that almost every protein in the cell undergoes some form of post?translational modification. We describe a protocol to use the scan?x Web site to view predicted acetylation sites in the human proteome and predicted
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