- ￥1750
- SIGMA
- 美国
- SRP6238-10UG
- 2025年07月14日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
瓶身
- 保质期：
coa
- 英文名：
SIGMA
- 库存：
999
- 供应商：
麦飞生物
- 规格：
SRP6238-10UG
说明
一般描述
TRAIL is a cytotoxic protein, which activates rapid apoptosis in tumor cells, but not in normal cells. TRAIL induced apoptosis is achieved through binding to two death-signaling receptors, DR4 and DR5. These receptors belong to the TNFR superfamily of transmembrane proteins and contain a cytoplasmic “death domain”, which activates the cell′s apoptotic machinery. Recombinant murine TRAIL is a 174 amino acid polypeptide (20.0 kDa), consisting of the TNF homologous portion of the extracellular domain of the full length TRAIL protein.
外形
Sterile filtered through a 0.2 micron filter. Lyophilized from 10 mM Sodium Phosphate, pH 7.0.
重悬
Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/mL. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.
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文献和实验Macrophage-expressed IFN-β contributes to apoptotic alveolar epithelial cell injury in severe influenza virus pneumonia.
Katrin Högner et al.
PLoS pathogens, 9(2), e1003188-e1003188 (2013-03-08)
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