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- 详细信息
- 文献和实验
- 技术资料
- 靶点:
TNFRSF8
- 应用范围:
WB 1:2000, IHC 1:150, FLOW 1:100
- 宿主:
Mouse
- 适应物种:
Human
- 保质期:
1-2年
- 供应商:
安诺伦(北京)生物科技有限公司
- 标记物:
Unconjugated
- 克隆性:
Monoclonal Antibody
- 保存条件:
Stable for 1 year at -20°C from date of shipment. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
- 形态:
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
- 亚型:
IgG1
- 免疫原:
Human recombinant protein fragment corresponding to amino acids 19-379 of human TNFRSF8 (NP_001234) produced in E.coli.
- 规格:
100 ug
产品概述:Carrier-free (BSA/glycerol-free) TNFRSF8 mouse monoclonal antibody, clone LBI1C6
总结:The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
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文献和实验Monoclonal Antibody Production
and screening of the hybridomas: 1. Bleeding Mice (1) Place the mouse in a mouse restrainer. (2) Sterilize the tail with 70% ethanol. (3) With a razor blade,nip off the last 2 mm of the tip of the tail. (4) Using a milking motion,pull blood down and let
Monoclonal Antibody Production
Monoclonal Antibody Production Mouse Immunization Order 6 six week old Balb/C mice and let the ARC know they are coming. Have your antigen ready for when they arrive. Once they get there earmark the mice and perform
Chimerization of a Monoclonal Antibody for Treating Hodgkin's Lymphoma
of the immunotoxin (6 ). In order to fully preserve the specificity of Ber-H2 and to overcome the aforementioned disadvantages, we have generated a chimeric mouse/human antibody.
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