Cellular Apoptosis Susceptibility (CSE1L) Mouse Monoclonal Antibody [Clone ID: LBI2C5]

Cellular Apoptosis Susceptibil

ity (CSE1L) Mouse Monoclonal Antibody [Clone ID: LBI2C5]
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  • ¥3300
  • Leading Biology
  • 美国
  • 2025年07月11日
  • WB 1:500
  • Mouse
  • Human, Mouse, Rat
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    • 详细信息
    • 技术资料
    • 靶点

      CSE1L

    • 应用范围

      WB 1:500

    • 宿主

      Mouse

    • 适应物种

      Human, Mouse, Rat

    • 保质期

      1-2年

    • 供应商

      安诺伦(北京)生物科技有限公司

    • 标记物

      Unconjugated

    • 克隆性

      Monoclonal Antibody

    • 保存条件

      Stable for 1 year at -20°C from date of shipment. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

    • 形态

      Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

    • 亚型

      IgG2b

    • 免疫原

      Human recombinant protein fragment corresponding to amino acids 1-300 of human CSE1L (NP_001307) produced in E.coli.

    • 规格

      100 ug

    别名:CAS; CSE1; XPO2

    产品概述:Carrier-free (BSA/glycerol-free) CSE1L mouse monoclonal antibody,clone LBI2C5

    总结:Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]

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