Alirocumab阿利西尤单抗阿利西尤单抗,1245916

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务。

Alirocumab

CAS No. : 1245916-14-6

MCE 国际站：Alirocumab

产品活性：Alirocumab (REGN 727) 是一种 PCSK9 的人单克隆抗体抑制剂。Alirocumab 是一种单克隆抗体。Alirocumab 有抗炎、抗血管生成和抗氧化作用。Alirocumab 可用于高胆固醇血症的研究。

研究领域：Metabolic Enzyme/Protease

作用靶点：Ser/Thr Protease

In Vitro: Alirocumab (0.01, 0.1, 1, 2 and 10 μM, 24-72 h) does not affect cell viability and function in hiPSC-CMs and hESC-CMs, and can be used to evaluate drug safety in lipid-lowering cardiovascular cells.

In Vivo: Alirocumab (3 or 10 mg/kg, subcutaneous injection weekly for 18 weeks) inhibits atherosclerosis, improves the plaque morphology, and enhances the effects of a statin.
Alirocumab (10 mg/kg, intraperitoneal injection at day 0, 10, 20) inhibits PCSK9 in rats and improves systemic oxidative stress and hyperlipidemia in BDL-induced cirrhosis rats.

相关产品：Leupeptin hemisulfate  |  Aprotinin  |  AEBSF hydrochloride  |  Camostat mesylate  |  WNK463  |  Proteinase K  |  Bradykinin  |  Nafamostat mesylate  |  PF-06446846 hydrochloride  |  Inclisiran  |  Trypsin  |  WNK-IN-11  |  Benzamidine hydrochloride  |  Evolocumab  |  SBC-115076  |  Chymotrypsin  |  Trypsin Inhibitor, soybean  |  Pep2-8  |  7-Amino-4-methylcoumarin  |  IPR-803  |  Avoralstat  |  R-IMPP  |  Berotralstat dihydrochloride  |  Bococizumab  |  UKI-1  |  UK122  |  BioE-1115  |  PCSK9-IN-12  |  Pinostrobin

热门产品线：重组蛋白  |  化合物库  |  天然产物  |  荧光染料  |  PROTAC  |  同位素标记物

Trending products：Recombinant Proteins  |  Bioactive Screening Libraries  |  Natural Products  |  Dye Reagents  |  PROTAC  |  Isotope-Labeled Compounds