Product Sheet
PD0325901, MEK Inhibitor Catalog # CB031-0181、CB031-0182、CB031-0183
Description A selective inhibitor against purified MEK, exhibiting a Ki of 1 nM against activated MEK1 and MEK2. It has been shown that 1 μM PD0325901 combined with 3 μM CHIR99021 (2i) prevents cell differentiation and sustains self-renewal of murine embryonic stem cells.
Formulation Powder
Reconstitution Before reconstitution, we recommend a brief spin to drive down any material dislodged from the bottom of the tube. The compound is soluble in DMSO.
Stability The powder is stable for at least 2 year if stored at -20 degree C. The dissolved compound is stable for at least 1 month at 4 degree C, but should be stored in aliquots at -20 degree C for longer term. Protect from light.
Purity Greater than 98% as determined by LC/MS analysis. LC/MS and/or NMR data available upon request.
Biological Activity Not determined.
Structural Info MW: 482.19
Formula: C16H14F3IN2O4
Solubility: Soluble in DMSO at 10 mM.
CAS: 391210-10-9
For Research Use Only. Not for Use in Humans.