![Constitutive androstane receptor (NR1I3) Mouse Monoclonal Antibody [Clone ID: LBI1C6]](https://img1.dxycdn.com/2022/0707/344/1496323853485278553-14.jpg)
- ￥3300
- Leading Biology
- AMM16874VCF
- 美国
- 2025年07月13日
- WB 1:2000, IHC 1:150
- Mouse
- Human
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- 详细信息
- 技术资料
- 靶点：
NR1I3
- 应用范围：
WB 1:2000, IHC 1:150
- 宿主：
Mouse
- 适应物种：
Human
- 保质期：
1-2年
- 供应商：
安诺伦（北京）生物科技有限公司
- 标记物：
Unconjugated
- 克隆性：
Monoclonal Antibody
- 保存条件：
Stable for 1 year at -20°C from date of shipment. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
- 形态：
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
- 亚型：
IgG1
- 免疫原：
Human recombinant protein fragment corresponding to amino acids 1-236 of human NR1I3 (NP_001070950) produced in E.coli.
- 规格：
100 ug
别名：CAR; CAR1; MB67
产品概述：Carrier-free (BSA/glycerol-free) NR1I3 mouse monoclonal antibody, clone LBI1C6
总结：This gene encodes a member of the nuclear receptor superfamily, and is a key regulator of xenobiotic and endobiotic metabolism. The protein binds to DNA as a monomer or a heterodimer with the retinoid X receptor and regulates the transcription of target genes involved in drug metabolism and bilirubin clearance, such as cytochrome P450 family members. Unlike most nuclear receptors, this transcriptional regulator is constitutively active in the absence of ligand but is regulated by both agonists and inverse agonists. Ligand binding results in translocation of this protein to the nucleus, where it activates or represses target gene transcription. These ligands include bilirubin, a variety of foreign compounds, steroid hormones, and prescription drugs. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
产品概述：Carrier-free (BSA/glycerol-free) NR1I3 mouse monoclonal antibody, clone LBI1C6
总结：This gene encodes a member of the nuclear receptor superfamily, and is a key regulator of xenobiotic and endobiotic metabolism. The protein binds to DNA as a monomer or a heterodimer with the retinoid X receptor and regulates the transcription of target genes involved in drug metabolism and bilirubin clearance, such as cytochrome P450 family members. Unlike most nuclear receptors, this transcriptional regulator is constitutively active in the absence of ligand but is regulated by both agonists and inverse agonists. Ligand binding results in translocation of this protein to the nucleus, where it activates or represses target gene transcription. These ligands include bilirubin, a variety of foreign compounds, steroid hormones, and prescription drugs. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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Constitutive androstane receptor (NR1I3) Mouse Monoclonal Antibody [Clone ID: LBI1C6]
￥3300
