Ntmt1 (NM_170592) Mouse Recomb

产品概述：Purified recombinant protein of Mouse N-terminal Xaa-Pro-Lys N-methyltransferase 1 (Ntmt1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug 蛋白长度：A DNA sequence from Mouse cDNA ORF Clone, [GM32362V], encoding Mouse full-length Ntmt1. 表达系统：HEK293T 种属：Mouse 标签类型：C-MYC/DDK 分子量：25.4 kDa 通用名：Ntmt1 总结：Distributive alpha-N-methyltransferase that methylates the N-terminus of target proteins containing the N-terminal motif [Ala/Gly/Pro/Ser]-Pro-Lys when the initiator Met is cleaved. Specifically catalyzes mono-, di- or tri-methylation of the exposed alpha-amino group of the Ala, Gly or Ser residue in the [Ala/Gly/Ser]-Pro-Lys motif and mono- or di-methylation of Pro in the Pro-Pro-Lys motif (PubMed:20668449). Some of the substrates may be primed by METTL11B-mediated monomethylation. Catalyzes the trimethylation of the N-terminal Gly in CENPA (after removal of Met-1) (By similarity). Responsible for the N-terminal methylation of KLHL31, MYL2, MYL3, RB1, RCC1, RPL23A and SET. Required during mitosis for normal bipolar spindle formation and chromosome segregation via its action on RCC1 (PubMed:20668449).[UniProtKB/Swiss-Prot Function] 形式：Liquid 浓度：>50 ug/mL as determined by microplate BCA method 纯度：> 80% as determined by SDS-PAGE and Coomassie blue staining 储存溶液：25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. 别名：2610205E22Rik; AL033331; AL033332; Mettl11a; NTM1A