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- 详细信息
- 文献和实验
- 技术资料
- 靶点:
HDLCQ11; LIPD
- 浓度:
Affinity purification
- 应用范围:
WB (Mus musculus)
- 宿主:
Rabbit
- 适应物种:
Human, Mouse
- 保质期:
1-2年
- 供应商:
安诺伦(北京)生物科技有限公司
- 保存条件:
Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
- 形态:
形式:Liquid 储存溶液:Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
- 亚型:
IgG
- 免疫原:
A synthesized peptide derived from human Lipoprotein lipase (LPL) (LPL)
- 规格:
50 µl/100 µl/200 µl
| 规格: | 50 µl | 产品价格: | ¥1650.0 |
|---|---|---|---|
| 规格: | 100 µl | 产品价格: | ¥2685.0 |
| 规格: | 200 µl | 产品价格: | ¥4230.0 |
Observed MW: 53KDa
细胞定位:Cell membrane, GPI-anchor, Lipid-anchor, Secreted
稀释方法:WB 1:500 - 1:2000
总结:LPL encodes lipoprotein lipase, which is expressed in heart, muscle, and adipose tissue. LPL functions as a homodimer, and has the dual functions of triglyceride hydrolase and ligand/bridging factor for receptor-mediated lipoprotein uptake. Severe mutations that cause LPL deficiency result in type I hyperlipoproteinemia, while less extreme mutations in LPL are linked to many disorders of lipoprotein metabolism. [provided by RefSeq, Jul 2008]
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文献和实验In Vitro Transcription and Translation of Lipoprotein Lipase
LPL is regulated post-transcriptionally in response to several hormones. Post-translational regulation occurs in response to feeding (1 ,2 ). Glycosylation of LPL at the first N-linked glycosylation site is essential for catalytic activity
Detecting Ligands Interacting with Lipoprotein Lipase
The primary role for lipoprotein lipase (LPL) is hydrolysis of triglycerides in chylomicrons and very low density lipoproteins (VLDL). This enzyme has also been implicated in the process of atherogenesis (for reviews see refs
Determining Lipoprotein Lipase and Hepatic Lipase Activity Using Radiolabeled Substrates
Hepatic lipase (HL) and lipoprotein lipase (LPL) are two lipolytic enzymes that play an important role in the metabolism of circulating lipoproteins. Both enzymes catalyze the esterolysis of fatty acids present at the sn -1 (3) position
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