万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 供应商:
优利科(上海)生命科学有限公司
- 库存:
100
- 靶点:
详询
- 级别:
科研
- 目录编号:
/
- 克隆性:
多克隆
- 抗原来源:
详见说明书
- 保质期:
1年
- 抗体英文名:
Anti-IGSF5
- 抗体名:
IGSF5抗体
- 标记物:
详询
- 宿主:
兔
- 适应物种:
/
- 免疫原:
见产品详情
- 亚型:
IgG
- 形态:
冻干或液体
- 应用范围:
见产品详情
- 保存条件:
-20℃
- 浓度:
1mg/ml
- 规格:
详询
| 英文名称 Anti-IGSF5 |
| 中文名称 免疫球蛋白超家族成员5抗体 |
| 别 名 GSF5; IgSF5; IGSF5_HUMAN; Immunoglobulin superfamily 5 like; Immunoglobulin superfamily member 5; JAM-4; Junctional adhesion molecule 4. |
| 浓 度 1mg/1ml |
| 规 格 0.2ml/200μg |
| 抗体来源 Rabbit |
| 克隆类型 polyclonal |
| 交叉反应 Human |
| 产品类型 一抗 |
研究领域 细胞生物 信号转导 细胞表面分子 ![]() |
| 蛋白分子量 predicted molecular weight: 45kDa |
| 性 状 Lyophilized or Liquid |
| 免 疫 原 KLH conjugated synthetic peptide derived from human IGSF5 |
| 亚 型 IgG |
| 纯化方法 affinity purified by Protein A |
| 储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 |
| 产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:100-500 ICC=1:100-500 IF=1:50-200 |
| (石蜡切片需做抗原修复) |
| not yet tested in other applications. |
| optimal dilutions/concentrations should be determined by the end user. |
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. ![]() |
| Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 Provides, together with MAGI1, an adhesion machinery at tight junctions, which may regulate the permeability of kidney glomerulus and small intestinal epithelial cells. Mediates calcium-independent homophilic cell adhesion. In testis, it may function as a cell adhesion molecule rather than a tight-junction protein. It may participate in the adhesion between spermatogonia-spermatogonia, spermatogonia-Sertoli cells, and Sertoli cells-Sertoli cells. |
| Function : Provides, together with MAGI1, an adhesion machinery at tight junctions, which may regulate the permeability of kidney glomerulus and small intestinal epithelial cells. Mediates calcium-independent homophilic cell adhesion. In testis, it may function as a cell adhesion molecule rather than a tight-junction protein. It may participate in the adhesion between spermatogonia-spermatogonia, spermatogonia-Sertoli cells, and Sertoli cells-Sertoli cells (By similarity). |
| Subunit : Interacts with MAGI1 at tight junctions, forms a tripartite complex with NPHS1 (By similarity). Interacts with LNX1 isoform 2 via its PDZ 2 domain, it may also interact with other isoforms containing this domain (By similarity). |
| Subcellular Location : Cell membrane; Single-pass membrane protein (By similarity). Cell junction, tight junction (By similarity). |
| Similarity : Belongs to the immunoglobulin superfamily. |
| Contains 2 Ig-like V-type (immunoglobulin-like) domains. |
Database links : UniProtKB/Swiss-Prot: Q9NSI5.2![]() |
| Anti-P-fscn1 (fascin homolog 1, actin-bundling protein) 磷酸化纤维束蛋白同源物1/肌动蛋白集束蛋白/圆线虫紫癜 抗体 |
| Anti-P-GP(P-glycoprotein) P-糖蛋白(抗体) |
| Anti-PGRN (progranulin) 颗粒蛋白前体抗体 |
| Anti-PI3K/P85 alpha(Phosphatidyl inositol 3-kinase) 磷脂酰肌醇激酶抗体 |
| Anti-PIBF(progesterone induced blocking factor) 孕激素诱导阻断因子抗体 |
| Anti-PIWIL1(piwi-like 1) piwi样1蛋白抗体 |
| Anti-PKA(Protein Kinase A) 蛋白激酶A抗体 |
| Anti-PKB/AKT-1(mouse) 蛋白激酶B(小鼠来源抗体) |
| Anti-PKC(Protein Kinase C) 蛋白激酶C抗体 |
| Anti-PLAU/uPA (Plasminogen activator,urokinase) 尿激酶型纤溶酶原激活因子抗体 |
| Anti-PLGF (Placenta growth factor human) 人胎盘生长因子(抗体)相关抗体 YT-0280R(抗大鼠) YT-0234R(抗小鼠) |
| Anti-PLGF (Placenta growth factor mouse) 小鼠胎盘生长因子抗体 |
| Anti-PLGF(Placenta growth factor for mouse rat and pig) 胎盘生长因子抗体: 相关抗体:YT-0281R(抗人) YT-0234R(抗小鼠) |
风险提示:丁香通仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验佚名 在参与细胞间相互识别、相互作用的粘附分子中,有许多分子具有与lgV区或C区相似的折叠结构,其氨基酸组成也有一定的同源性,属于免疫球蛋白超家族(immunogiobulin superfamily,IGSF)的成员。免疫球蛋白超家族粘附分子的种类、分布及其配体见表6-4。免疫球蛋白超家族粘附分子的配体多为免疫球蛋白超家族中的粘附分子或粘合素超家族的粘附
区(C区)有较高的同源性,它们可能从同一祖先基因(primordial ancestral gene)进化而来。编码这些多肽链的基因称为免疫球蛋白基因超家族(immunoglobulin gene superfamily),这一基因超家族所编码的产物称为免疫球蛋白超家族(immunoglobulin superfamily,IGSF)。 Ig超家族中某些成员如Fascilin Neuroglian和Amalgam等分子存在于昆虫中,这表明Ig超家族结构域的多样
链的基因称为免疫球蛋白基因超家族(immunoglobulin gene superfamily),这一基因超家族所编码的产物称为免疫球蛋白超家族(immunoglobulin superfamily,IGSF)。 Ig超家族中某些成员如Fascilin Neuroglian和Amalgam等分子存在于昆虫中,这表明Ig超家族结构域的多样化(diversification)在后生动物(Metazoon)进化早期即开始发生,通过基因的复制(duplication)和随后发生的偏离













